Articles with "anoikis resistance" as a keyword



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Astrocyte elevated gene 1 (AEG‐1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29377

Abstract: Astrocyte elevated gene 1 (AEG‐1) is overexpressed in hepatocellular carcinoma (HCC) and is strongly associated with tumor metastasis. Anoikis resistance and autophagy may play an important role in the survival of circulating tumor cells. However,… read more here.

Keywords: aeg; hcc; metastasis; astrocyte elevated ... See more keywords

Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis

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Published in 2021 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-021-02867-x

Abstract: The aim of this study was to investigate the role of IL-17A in the cancer microenvironment and the recurrence of triple negative breast cancer (TNBC). Using human TNBC cell lines, the role of IL17-A was… read more here.

Keywords: anoikis resistance; expression; cancer; triple negative ... See more keywords
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Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis

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Published in 2019 at "Molecular and Cellular Biochemistry"

DOI: 10.1007/s11010-019-03547-2

Abstract: In the present study, we intend to determine whether Sestrin proteins 1, 2, and 3 (SESN1-3) are targets of microRNA-200 family (miR-200) in endometrial cancer (EC) Ishikawa, AN3CA, KLE, and RL 95-2 cell lines and… read more here.

Keywords: sestrin proteins; cell lines; mir 200; anoikis resistance ... See more keywords
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BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling.

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Published in 2021 at "Journal of cell communication and signaling"

DOI: 10.1007/s12079-021-00649-9

Abstract: Bone morphogenetic proteins (BMPs) regulate cell fate during development and mediate cancer progression. In this study, we investigated the role of BMP4 in proliferation, anoikis resistance, metastatic migration, and drug resistance of breast cancer cells.… read more here.

Keywords: cancer; anoikis resistance; cancer cells; breast cancer ... See more keywords
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Kallistatin Inhibits Anoikis Resistance and Metastasis of Ectopic Endometrium Cells by Modulating MnSOD and Caspase 3 Signaling

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Published in 2021 at "Reproductive Sciences"

DOI: 10.1007/s43032-020-00421-1

Abstract: Endometriosis (EM) is a disease that involves active endometrial cell invasion and migration which is an important reason for infertility. Anoikis resistance is the most important prerequisite for EM, but the molecular mechanism is not… read more here.

Keywords: metastasis; ectopic endometrium; mnsod caspase; anoikis resistance ... See more keywords
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ZNF32 induces anoikis resistance through maintaining redox homeostasis and activating Src/FAK signaling in hepatocellular carcinoma.

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Published in 2019 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.09.033

Abstract: Tumor cells need to attain anoikis resistance to survive prior to metastasis making it a vital trait of malignancy. The molecular mechanism by which hepatocellular carcinoma (HCC) cells resist anoikis remains not fully understood. Here,… read more here.

Keywords: hcc; fak signaling; anoikis resistance; znf32 ... See more keywords
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BRN2 expression increases anoikis resistance in melanoma

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Published in 2020 at "Oncogenesis"

DOI: 10.1038/s41389-020-00247-1

Abstract: Melanoma tumors are highly heterogeneous, comprising of many cell populations that vary in their potential for growth and invasion. Differential transcription factor expression contributes to these phenotypic traits. BRN2, a member of the POU domain… read more here.

Keywords: melanoma; anoikis resistance; expression; brn2 expression ... See more keywords
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IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma

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Published in 2020 at "British Journal of Cancer"

DOI: 10.1038/s41416-020-0970-z

Abstract: Background Hepatitis B virus (HBV) has a crucial role in the progression of hepatocellular carcinoma (HCC). Tumour cells must develop anoikis resistance in order to survive before metastasis. This study aimed to investigate the mechanism… read more here.

Keywords: iqgap1; hbv; metastasis; anoikis resistance ... See more keywords
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The inhibitory effect of microRNA-1827 on anoikis resistance in lung adenocarcinoma A549 cells via targeting caveolin-1.

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Published in 2020 at "Acta biochimica et biophysica Sinica"

DOI: 10.1093/abbs/gmaa102

Abstract: Anoikis resistance is a critical process for cancer cell metastasis in non-small cell lung cancer (NSCLC), and microRNA-1827 (miR-1827) is closely correlated with NSCLC metastasis. In this study, we aimed to evaluate the role of… read more here.

Keywords: a549 cells; anoikis resistance; resistance; microrna 1827 ... See more keywords
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Long noncoding RNA MRPL23-AS1 suppresses anoikis in salivary adenoid cystic carcinoma in vitro.

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Published in 2022 at "Oral diseases"

DOI: 10.1111/odi.14156

Abstract: Distant lung metastasis is the main factor that affects the survival rate of patients with salivary adenoid cystic carcinoma (SACC). Anoikis resistance is a feature of tumor cells that easily metastasize. The long non-coding RNA… read more here.

Keywords: sacc; anoikis resistance; as1; mprl23 as1 ... See more keywords
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Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells

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Published in 2021 at "International Journal of Endocrinology"

DOI: 10.1155/2021/5583491

Abstract: Accumulating evidence suggests that galectin-3 is a histologic marker of thyroid cancer. However, the pharmacological lectin-based approach has not been well studied. In the present study, we aimed to investigate the therapeutic potential of novel… read more here.

Keywords: thyroid cancer; anoikis resistance; galectin inhibitors; cancer cells ... See more keywords