Involvement of PDGFR‐integrin interactions in the regulation of anoikis resistance in glioblastoma progression
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biology International"
DOI: 10.1002/cbin.12257
Abstract: The interactions between platelet‐derived growth factor/PDGF receptor and integrin signaling are crucial for cells to respond to extracellular stimuli. Integrin interactions with PDGFR within the lipid rafts activate downstream cellular signaling pathways that regulate cell… read more here.
Keywords: anoikis resistance; glioblastoma progression; pdgfr integrin; cell ... See more keywords
Astrocyte elevated gene 1 (AEG‐1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29377
Abstract: Astrocyte elevated gene 1 (AEG‐1) is overexpressed in hepatocellular carcinoma (HCC) and is strongly associated with tumor metastasis. Anoikis resistance and autophagy may play an important role in the survival of circulating tumor cells. However,… read more here.
Keywords: aeg; hcc; metastasis; astrocyte elevated ... See more keywords
Downregulation of HTRA1 Promotes EMT and Anoikis Resistance in Colorectal Cancer via Activation of Hippo/YAP1 Pathway by Facilitating LATS2 Degradation
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23933
Abstract: Epithelial‐mesenchymal transition (EMT) and anoikis resistance are crucial characteristics for tumor cell metastasis. High‐temperature requirement A1 (HTRA1) has been identified as a serine protease with chaperone functions, but its role in the regulation of EMT,… read more here.
Keywords: emt anoikis; anoikis resistance; yap1; hippo ... See more keywords
SERPINE1 Facilitates Metastasis in Gastric Cancer Through Anoikis Resistance and Tumor Microenvironment Remodeling.
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DOI: 10.1002/smll.202500136
Abstract: SERPINE1 is a serine protease inhibitor upregulated in various malignancies and pivotal in gastric cancer (GC) metastasis and the tumor microenvironment (TME). This study elucidates the mechanisms by which SERPINE1 mediates anoikis resistance and fosters… read more here.
Keywords: resistance; serpine1 facilitates; anoikis resistance; tumor microenvironment ... See more keywords
Interleukin 17A promotes cell migration, enhances anoikis resistance, and creates a microenvironment suitable for triple negative breast cancer tumor metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02867-x
Abstract: The aim of this study was to investigate the role of IL-17A in the cancer microenvironment and the recurrence of triple negative breast cancer (TNBC). Using human TNBC cell lines, the role of IL17-A was… read more here.
Keywords: anoikis resistance; expression; cancer; triple negative ... See more keywords
Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03547-2
Abstract: In the present study, we intend to determine whether Sestrin proteins 1, 2, and 3 (SESN1-3) are targets of microRNA-200 family (miR-200) in endometrial cancer (EC) Ishikawa, AN3CA, KLE, and RL 95-2 cell lines and… read more here.
Keywords: sestrin proteins; cell lines; mir 200; anoikis resistance ... See more keywords
BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell communication and signaling"
DOI: 10.1007/s12079-021-00649-9
Abstract: Bone morphogenetic proteins (BMPs) regulate cell fate during development and mediate cancer progression. In this study, we investigated the role of BMP4 in proliferation, anoikis resistance, metastatic migration, and drug resistance of breast cancer cells.… read more here.
Keywords: cancer; anoikis resistance; cancer cells; breast cancer ... See more keywords
Kallistatin Inhibits Anoikis Resistance and Metastasis of Ectopic Endometrium Cells by Modulating MnSOD and Caspase 3 Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00421-1
Abstract: Endometriosis (EM) is a disease that involves active endometrial cell invasion and migration which is an important reason for infertility. Anoikis resistance is the most important prerequisite for EM, but the molecular mechanism is not… read more here.
Keywords: metastasis; ectopic endometrium; mnsod caspase; anoikis resistance ... See more keywords
ZNF32 induces anoikis resistance through maintaining redox homeostasis and activating Src/FAK signaling in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.09.033
Abstract: Tumor cells need to attain anoikis resistance to survive prior to metastasis making it a vital trait of malignancy. The molecular mechanism by which hepatocellular carcinoma (HCC) cells resist anoikis remains not fully understood. Here,… read more here.
Keywords: hcc; fak signaling; anoikis resistance; znf32 ... See more keywords
BRN2 expression increases anoikis resistance in melanoma
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DOI: 10.1038/s41389-020-00247-1
Abstract: Melanoma tumors are highly heterogeneous, comprising of many cell populations that vary in their potential for growth and invasion. Differential transcription factor expression contributes to these phenotypic traits. BRN2, a member of the POU domain… read more here.
Keywords: melanoma; anoikis resistance; expression; brn2 expression ... See more keywords
IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-0970-z
Abstract: Background Hepatitis B virus (HBV) has a crucial role in the progression of hepatocellular carcinoma (HCC). Tumour cells must develop anoikis resistance in order to survive before metastasis. This study aimed to investigate the mechanism… read more here.
Keywords: iqgap1; hbv; metastasis; anoikis resistance ... See more keywords