Cardiac natriuretic peptide deficiency sensitizes the heart to stress induced ventricular arrhythmias via impaired CREB signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular research"
DOI: 10.1093/cvr/cvab257
Abstract: AIMS The cardiac natriuretic peptides (atrial natriuretic peptide [ANP] and B-type natriuretic peptide [BNP]) are important regulators of cardiovascular physiology, with reduced natriuretic peptide (NP) activity linked to multiple human cardiovascular diseases. We hypothesized that… read more here.
Keywords: ventricular arrhythmias; natriuretic peptide; stress; anp bnp ... See more keywords
Abstract 13027: Differential Direct Effects of Equal Hypotensive Natriuretic Peptides (NPs) of ANP, BNP and CNP on Left Ventricular Contractile Performance in Heart Failure: Assessment by Left Ventricular Pressure-Volume Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.13027
Abstract: Background: Natriuretic peptides (NPs) play a crucial role in maintaining cardiovascular homeostasis. NPs stimulate the production and release of cGMP, leading to the vasodilating and natriuretic actions. In heart failure (HF), circulating and cardiac ANP,… read more here.
Keywords: bnp; cnp; heart; bnp cnp ... See more keywords
The Atrial Natriuretic Peptide-to-brain Natriuretic Peptide Ratio Predicts Left Atrial Reverse Remodeling after Rhythm Control Therapy in Patients with Persistent Atrial Fibrillation.
Sign Up to like & getrecommendations! Published in 2023 at "Internal medicine"
DOI: 10.2169/internalmedicine.1478-22
Abstract: Objective The association between natriuretic peptide levels in atrial fibrillation (AF) patients with advanced left atrial (LA) remodeling and reverse remodeling after rhythm control therapy has not been clarified. The present study assessed the role… read more here.
Keywords: reverse remodeling; natriuretic peptide; anp bnp; rhythm control ... See more keywords
Clinical and pathogenetic importance of hormonal natriuretic peptides in gout
Sign Up to like & getrecommendations! Published in 2018 at "INTERNATIONAL JOURNAL OF ENDOCRINOLOGY"
DOI: 10.22141/2224-0721.14.5.2018.142683
Abstract: Актуальність. Окрім порушень пуринового обміну, систем прозапальних цитокінів, матриксних металопротеїназ та ейкозаноїдів, в патогенезі подагри можуть брати участь різні середньомолекулярні поєднання, у тому числі натрійуретичні пептиди (передсердний — ANP, мозковий — BNP), але їх значущість… read more here.
Keywords: anp; pathogenetic importance; bnp anp; clinical pathogenetic ... See more keywords
CNP, the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular System
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DOI: 10.3390/biology11070986
Abstract: Simple Summary CNP is the third natriuretic peptide to be isolated and is widely expressed in the central nervous system, osteochondral system, and vascular system. The receptor that is mainly targeted by CNP is GC-B,… read more here.
Keywords: cardiovascular system; system; natriuretic peptide; cnp ... See more keywords
Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases
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DOI: 10.3390/biology11071017
Abstract: Simple Summary The endocrine effects of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in the vasculature, and the autocrine effects of ANP and BNP in cardiomyocytes are mediated by the common guanylyl cyclase… read more here.
Keywords: roles natriuretic; natriuretic peptide; anp bnp; natriuretic peptides ... See more keywords
NRSF/REST-Mediated Epigenomic Regulation in the Heart: Transcriptional Control of Natriuretic Peptides and Beyond
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DOI: 10.3390/biology11081197
Abstract: Simple Summary Reactivation of the fetal cardiac gene program, such as those encoding atrial and brain natriuretic peptides (ANP and BNP, respectively), is a characteristic feature of failing hearts. We previously revealed that a transcriptional… read more here.
Keywords: anp bnp; repressor; regulation; heart ... See more keywords
Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP Generation
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DOI: 10.3390/ijms24108547
Abstract: The natriuretic peptide system (NPS) and renin-angiotensin-aldosterone system (RAAS) function oppositely at multiple levels. While it has long been suspected that angiotensin II (ANGII) may directly suppress NPS activity, no clear evidence to date supports… read more here.
Keywords: cyclase receptor; anp bnp; guanylyl cyclase; evidence ... See more keywords
Telmisartan suppresses cardiac hypertrophy by inhibiting cardiomyocyte apoptosis via the NFAT/ANP/BNP signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2017.6318
Abstract: Telmisartan, a type of angiotensin II (Ang II) receptor inhibitor, is a common agent used to treat hypertension in the clinic. Hypertension increases cardiac afterload and promotes cardiac hypertrophy. However, the ventricular Ang II receptor… read more here.
Keywords: cardiomyocyte apoptosis; cardiac hypertrophy; hypertrophy; anp bnp ... See more keywords