Long‐term ANT‐DBS effects in pilocarpine‐induced epileptic rats: A combined 9.4T MRI and histological study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25169
Abstract: Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) appears to be effective against seizures in animals and humans however, its therapeutic mechanisms remain elusive. This study aimed to combine 9.4T multimodal… read more here.
Keywords: epileptic rats; long term; dbs; ant dbs ... See more keywords
Effects of anterior thalamic nuclei stimulation on gene expression in a rat model of temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-019-01240-1
Abstract: Deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) has been shown to be effective and safe in the long-term treatment of refractory epilepsy. However, the mechanisms by which ANT-DBS controls epilepsy at… read more here.
Keywords: epilepsy; lobe epilepsy; group; ant dbs ... See more keywords
Deep brain stimulation of the anterior nucleus of the thalamus reverses the gene expression of cytokines and their receptors as well as neuronal degeneration in epileptic rats
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2016.12.020
Abstract: BACKGROUND Deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) is effective in seizure control. However, the mechanisms remain unclear. METHODS Sixty-four rats were randomly assigned to the control group, the kainic acid… read more here.
Keywords: group; dbs group; dbs; ant dbs ... See more keywords
FV 7 High-frequency anterior thalamus stimulation increases alertness in epilepsy patients during alert- and drowsy-wakefulness
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2017.06.049
Abstract: Objective Deep brain stimulation (DBS) of anterior thalamic nuclei (ANT) reduces frequency and intensity of epileptic partial and secondarily-generalized seizures. ANT-DBS disrupts sleep in epilepsy patients. We investigated the impact of ANT-DBS on alertness in… read more here.
Keywords: frequency; stimulation; dbs; ant dbs ... See more keywords
Comparison of efficiency between VNS and ANT-DBS therapy in drug-resistant epilepsy: A one year follow up study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2021.05.046
Abstract: Vagus nerve stimulation (VNS) and anterior thalamic deep brain stimulation (ANT-DBS) have both been used for treatments of drug-resistant epilepsy (DRE). However, there is no comparative study on the effectiveness of two methods from one… read more here.
Keywords: epilepsy; vns; age; study ... See more keywords
Cognitive change after DBS in refractory epilepsy: A randomized-controlled trial.
Sign Up to like & getrecommendations! Published in 2021 at "Acta neurologica Scandinavica"
DOI: 10.1111/ane.13539
Abstract: OBJECTIVES Deep brain stimulation of the anterior thalamic nucleus (ANT-DBS) reduces seizure frequency in patients with refractory epilepsy. There are, however, few studies on treatment-related changes in cognitive functions. The main objective of this study… read more here.
Keywords: refractory epilepsy; seizure frequency; stimulation; change ... See more keywords
ANT‐DBS in epilepsy shows no effect on selected neuropsychiatric tests
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.13658
Abstract: Deep brain stimulation of the anterior thalamic nucleus (ANT‐DBS) is an established option in treatment‐resistant epilepsy and obtained FDA approval in 2018. Increased psychiatric comorbidity is well known in epilepsy. The main objective of this… read more here.
Keywords: shows effect; dbs; epilepsy shows; ant dbs ... See more keywords