Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation
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DOI: 10.1186/s10020-019-0081-6
Abstract: BackgroundExtracellular high mobility group box 1 protein (HMGB1) serves a central role in inflammation as a transporter protein, which binds other immune-activating molecules that are endocytosed via the receptor for advanced glycation end-products (RAGE). These pro-inflammatory… read more here.
Keywords: hmgb1; hmgb1 antagonist; antagonist box; anti hmgb1 ... See more keywords