Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats
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DOI: 10.1016/j.nbd.2022.105610
Abstract: Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats was associated with increased GR signaling and changes in GR-mediated… read more here.
Keywords: antagonist mifepristone; dependent rats; withdrawal; alcohol ... See more keywords