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Confirmation of the Cardiac Safety of PGF2α Receptor Antagonist OBE022 in a First‐in‐Human Study in Healthy Subjects, Using Intensive ECG Assessments

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Published in 2018 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.447

Abstract: OBE022, a new orally active prostaglandin F2α receptor antagonist (OBE022) with myometrial selectivity is being developed to reduce uterine contractions during preterm labor. This first‐in‐human study evaluated the effect of OBE022 following multiple doses on… read more here.

Keywords: receptor antagonist; study; effect; human study ... See more keywords