Discovery of P2Y2 Receptor Antagonist Scaffolds through Virtual High-Throughput Screening
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DOI: 10.1021/acs.jcim.1c01235
Abstract: The human ATP- and UTP-activated P2Y2 receptor (P2Y2R) is a Gq protein-coupled receptor involved in several pathophysiological conditions including acute and chronic inflammation, cancer, and pain. Despite its potential as a novel drug target, only… read more here.
Keywords: virtual high; throughput screening; antagonist scaffolds; high throughput ... See more keywords