Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology
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DOI: 10.1021/jacs.7b11422
Abstract: Noninvasive methods to modulate G protein-coupled receptors (GPCRs) with temporal and spatial precision are in great demand. Photopharmacology uses photons to control in situ the biological properties of photoswitchable small-molecule ligands, which bodes well for… read more here.
Keywords: gpcr; antagonist toolbox; real time; photopharmacology ... See more keywords