Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model
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DOI: 10.1073/pnas.2202236119
Abstract: Significance X-linked centronuclear myopathy (XLCNM) is a severe human disease characterized by muscle fiber defects that result from mutations in the gene encoding the lipid phosphatase MTM1. At present there are no approved therapies for… read more here.
Keywords: antagonistic control; surface; kinase; model ... See more keywords