Examination of Charge Modifications of an Endolysosomal Trapping Inhibitor in an Antagonistic NTSR1-Targeted Construct for Colon Cancer.
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DOI: 10.1021/acs.bioconjchem.2c00214
Abstract: Many low-molecular weight targeted radiotherapeutics (TRTs) are capable of rapidly achieving exceptional tumor to non-target ratios shortly after administration. However, the low tumor residence time of many TRTs limits therapeutic dose delivery and has become… read more here.
Keywords: antagonistic ntsr1; charge; colon cancer; endolysosomal trapping ... See more keywords