Anterior gradient 2 is involved in the post-transcriptional regulation of β-dystroglycan
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DOI: 10.1080/19768354.2020.1871405
Abstract: ABSTRACT Anterior gradient 2 (AGR2) is a protein disulfide isomerase over-expressed in numerous types of cancer. Although AGR2 plays a role in ER homeostasis, its function(s) in tumorigenesis is still elusive. Here we demonstrate that… read more here.
Keywords: agr2; anterior gradient; cytoskeletal network; expression ... See more keywords
Inhibitory Effect of Etravirine, a Non-Nucleoside Reverse Transcriptase Inhibitor, via Anterior Gradient Protein 2 Homolog Degradation against Ovarian Cancer Metastasis
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DOI: 10.3390/ijms23020944
Abstract: Anterior gradient protein 2 homolog (AGR2), an endoplasmic reticulum protein, is secreted in the tumor microenvironment. AGR2 is a member of the disulfide isomerase family, is highly expressed in multiple cancers, and promotes cancer metastasis.… read more here.
Keywords: gradient protein; protein homolog; cancer metastasis; anterior gradient ... See more keywords