Anthracycline‐induced cardiomyopathy: secrets and lies
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DOI: 10.1002/ejhf.1172
Abstract: A growing number of cancer patients survive of cancer and one third of them will eventually die of heart disease that is at least partly related to cancer and its therapy.1,2 The recognition of this… read more here.
Keywords: heart; anthracycline induced; cancer; oncology ... See more keywords
Anthracycline-induced cardiotoxicity and renin-angiotensin-aldosterone system—from molecular mechanisms to therapeutic applications
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DOI: 10.1007/s10741-020-09977-1
Abstract: Few millions of new cancer cases are diagnosed worldwide every year. Due to significant progress in understanding cancer biology and developing new therapies, the mortality rates are decreasing with many of patients that can be… read more here.
Keywords: system; angiotensin aldosterone; anthracycline induced; renin angiotensin ... See more keywords
Molecular imaging of free radicals for anthracycline-induced cardiotoxicity: See the burn?
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DOI: 10.1007/s12350-020-02254-6
Abstract: The prognosis of patients with cancer has significantly improved in the past 20 years; thanks to optimization of chemotherapy protocols with established drugs, and the availability of molecules targeting new biological pathways. As cancer and… read more here.
Keywords: anthracycline induced; imaging free; anti neoplastic; cardiotoxicity ... See more keywords
Serial Magnetic Resonance Imaging to Identify Early Stages of Anthracycline-Induced Cardiotoxicity.
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DOI: 10.1016/j.jacc.2018.11.046
Abstract: BACKGROUND Anthracycline-induced cardiotoxicity is a major clinical problem, and early cardiotoxicity markers are needed. OBJECTIVES The purpose of this study was to identify early doxorubicin-induced cardiotoxicity by serial multiparametric cardiac magnetic resonance (CMR) and its… read more here.
Keywords: induced cardiotoxicity; anthracycline induced; magnetic resonance; cardiotoxicity ... See more keywords
Anthracycline-induced cardiotoxicity: molecular and genetic predictors for risk assessment
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DOI: 10.1093/ehjci/ehaa946.1146
Abstract: The objective of this study was to evaluate the role of molecular and genetic biomarkers in the development of anthracycline-induced cardiotoxicity in women with breast cancer at the 12 months after polychemotherapy. A total of… read more here.
Keywords: anthracycline induced; induced cardiotoxicity; breast cancer;
123I‐MIBG imaging for detection of anthracycline‐induced cardiomyopathy
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DOI: 10.1111/cpf.12419
Abstract: Due to improvements in early detection and treatment of malignant disease, the population of cancer survivors is constantly expanding. Cancer survivors are faced with chemotherapy‐related long‐term side effects, including irreversible cardiac injury with risk of… read more here.
Keywords: detection; 123i mibg; anthracycline induced; induced cardiomyopathy ... See more keywords
Early anthracycline‐induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs‐cTnT
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DOI: 10.1111/echo.13704
Abstract: As growing numbers of long‐term cancer survivors faced with the cardiac side effects by anthracycline treatment, it is necessary to explore the optimal monitoring method for the early detection of cardiac toxicity. read more here.
Keywords: induced cardiotoxicity; echocardiographic doppler; anthracycline induced; early anthracycline ... See more keywords
The Role of Mitochondrial Quality Control in Anthracycline-Induced Cardiotoxicity: From Bench to Bedside
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DOI: 10.1155/2022/3659278
Abstract: Cardiotoxicity is the major side effect of anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and the mainstay of therapy in solid and hematological neoplasms. Advances in the field… read more here.
Keywords: quality control; role; anthracycline induced; cardiotoxicity ... See more keywords
Current Status and Trends of Research on Anthracycline-Induced Cardiotoxicity from 2002 to 2021: A Twenty-Year Bibliometric and Visualization Analysis
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DOI: 10.1155/2022/6260243
Abstract: Anthracyclines constitute the cornerstone of numerous chemotherapy regimens for various cancers. However, the clinical application of anthracyclines is significantly limited to their dose-dependent cardiotoxicity. A comprehensive understanding of the current status of anthracycline-induced cardiotoxicity is… read more here.
Keywords: induced cardiotoxicity; anthracycline induced; status; cardiotoxicity ... See more keywords
Protective Effects of ACEI/ARB on Left Ventricular Function in Anthracycline-Induced Chronic Cardiotoxicity: A Meta-Analysis of Randomized Controlled Trials
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DOI: 10.1159/000512848
Abstract: Purpose: Cardiotoxicity is an important side effect of anthracycline. Cardioprotective drugs for anthracycline remain inconclusive. We attempted to determine the role of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-receptor blockers (ARB) in the prevention of anthracycline-induced… read more here.
Keywords: randomized controlled; acei arb; anthracycline induced; cardiotoxicity ... See more keywords
Abstract 195: Epigenetic Mechanisms Underlying Anthracycline-Induced Cardiotoxicity
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DOI: 10.1161/res.125.suppl_1.195
Abstract: Anthracycline-induced cardiotoxicity (AC) is a major cause of morbidity in childhood cancer survivors. Doxorubicin cardiotoxicity however, is consistently observed to develop chronically over time. We sought to develop a mouse model of pediatric AC to… read more here.
Keywords: anthracycline induced; cardiotoxicity; dox mice; induced cardiotoxicity ... See more keywords