Overproduction of L‐tryptophan via simultaneous feed of glucose and anthranilic acid from recombinant Escherichia coli W3110: Kinetic modeling and process scale‐up
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26398
Abstract: L‐tryptophan is an essential amino acid widely used in food and pharmaceutical industries. However, its production via Escherichia coli fermentation suffers severely from both low glucose conversion efficiency and acetic acid inhibition, and to date… read more here.
Keywords: escherichia coli; anthranilic acid; process; acid ... See more keywords
Anthranilic Acid Accumulation in Saccharomyces cerevisiae Induced by Expression of a Nonribosomal Peptide Synthetase Gene from Paecilomyces cinnamomeus BCC 9616
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200573
Abstract: Heterologous expression of nrps33, a nonribosomal peptide synthetase gene, from Paecilomyces cinnamomeus BCC 9616 in Saccharomyces cerevisiae unexpectedly resulted in the accumulation of anthranilic acid, an intermediate in tryptophan biosynthesis. Based on transcriptomic and real‐time… read more here.
Keywords: peptide synthetase; synthetase gene; anthranilic acid; accumulation ... See more keywords
Medicinal chemistry of anthranilic acid derivatives: A mini review.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21842
Abstract: Anthranilic acid and its analogues present a privileged profile as pharmacophores for the rational development of pharmaceuticals deliberated for managing the pathophysiology and pathogenesis of various diseases. The substitution on anthranilic acid scaffold provides large… read more here.
Keywords: derivatives anthranilic; chemistry; anthranilic acid; acid derivatives ... See more keywords
Biotransformations of anthranilic acid and phthalimide to potent antihyperlipidemic alkaloids by the marine-derived fungus Scedosporium apiospermum F41-1.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105375
Abstract: A new diphenylamine derivative, scediphenylamine A (1), together with six phthalimide derivatives (2-7) and ten other known compounds (8-17) were obtained from the marine-derived fungus Scedosporium apiospermum F41-1 fed with synthetically prepared anthranilic acid and… read more here.
Keywords: derived fungus; scedosporium apiospermum; apiospermum f41; anthranilic acid ... See more keywords
Practical approach to 2-thioxo-2,3-dihydroquinazolin-4(1H)-one via dithiocarbamate–anthranilic acid reaction
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2016.06.012
Abstract: A practical and straightforward protocol has been developed for the preparation of 2-thioxo-2,3-dihydroquinazolin-4(1H)-one derivatives from dithiocarbamate chemistry. The method involves the reaction of anthranilic acid derivatives (2-aminobenzoic acid, 2-aminobenzamide and isatoic anhydride) with various dithiocarbamate… read more here.
Keywords: dithiocarbamate; thioxo dihydroquinazolin; dihydroquinazolin one; anthranilic acid ... See more keywords
Highly bluish-white light emissive and redox active conjugated poly-N-phenyl anthranilic acid polymer fluoroprobe for analytical sensing
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DOI: 10.1016/j.polymer.2019.121747
Abstract: Abstract An efficient fluorescent and redox type conjugated poly-N-phenyl anthranilic acid (PNPA) was synthesised via chemical oxidative polymerisation of N-phenyl anthranilic acid (NPA) using FeCl3 as oxidising agent in ethanol medium. The polymer in sulphuric… read more here.
Keywords: bluish white; fluorescence; redox; polymer ... See more keywords
Conductive thin films based on poly (aniline-co-o-anthranilic acid)/magnetite nanocomposite for photovoltaic applications
Sign Up to like & getrecommendations! Published in 2017 at "Synthetic Metals"
DOI: 10.1016/j.synthmet.2017.06.021
Abstract: Abstract In this research, magnetite particles in a nanoscale were coated with three various weight percentages of poly (aniline co- o -anthranilic acid) copolymer. Aniline and o -anthranilic acid monomers were copolymerized in the presence… read more here.
Keywords: magnetite nanocomposite; thin films; anthranilic acid; aniline anthranilic ... See more keywords
Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01350
Abstract: Polyamine biosynthesis is regulated by ornithine decarboxylase (ODC), which is transcriptionally activated by c-Myc. A large library was screened to find molecules that potentiate the ODC inhibitor, difluoromethylornithine (DFMO). Anthranilic acid derivatives were identified as… read more here.
Keywords: binding protein; adjunct agents; far upstream; anthranilic acid ... See more keywords
A diarylamine derived from anthranilic acid inhibits ZIKV replication
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-54169-z
Abstract: Zika virus (ZIKV) is a mosquito-transmitted Flavivirus, originally identified in Uganda in 1947 and recently associated with a large outbreak in South America. Despite extensive efforts there are currently no approved antiviral compounds for treatment… read more here.
Keywords: diarylamine derived; anthranilic acid; acid inhibits; derived anthranilic ... See more keywords
Facile synthesis and fabrication of a poly(ortho-anthranilic acid) emeraldine salt thin film for solar cell applications
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c8nj01204k
Abstract: Poly(o-anthranilic acid) emeraldine salt (PANA-ES) as a conjugated semiconductor polymer has been synthesized in an acidic medium based oxidative polymerization route. The identification of the PANA-ES powder has been carried out using the following techniques:… read more here.
Keywords: pana; acid emeraldine; emeraldine salt; thin film ... See more keywords
Ca-, Sr-, and Ba-Coordination polymers based on anthranilic acid via mechanochemistry.
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DOI: 10.1039/c9dt00991d
Abstract: Ca-, Sr-, and Ba-Based coordination polymers (CPs) were prepared mechanochemically by milling metal-hydroxide samples with anthranilic acid (oABAH). {[Ca(oABA)2(H2O)3]}n (1) consists of one-dimensional polymeric chains that are further connected by a hydrogen-bonding network. {[Sr(oABA)2(H2O)2]·H2O}n (2)… read more here.
Keywords: anthranilic acid; oaba h2o; coordination; coordination polymers ... See more keywords