Synthesis and biological evaluation of dithiocarbamate esters of parthenolide as potential anti-acute myelogenous leukaemia agents
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DOI: 10.1080/14756366.2018.1490734
Abstract: Abstract A series of dithiocarbamate esters of parthenolide (PTL) was designed, synthesised, and evaluated for their anti- acute myelogenous leukaemia (AML) activities. The most promising compound 7l showed greatly improved potency against AML progenitor cell… read more here.
Keywords: myelogenous leukaemia; esters parthenolide; dithiocarbamate esters; leukaemia ... See more keywords