Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5020-9
Abstract: BackgroundInteractions between thiopurines and infliximab presumably contribute to superior effect of infliximab–thiopurine combination therapy in patients with inflammatory bowel disease (IBD). We examined whether principal cytotoxic thiopurine metabolites influence adalimumab (ADL) and anti-ADL antibodies (Abs).MethodsNinety-eight… read more here.
Keywords: thiopurine metabolites; anti adl; patients inflammatory; adl ... See more keywords
SAT0192 Competitive elisa and bridging elisa with acid dissociation detect anti-drug antibodies in a greater proportion of patients treated with tnf-Αlpha inhibitors than classical bridging elisa
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6486
Abstract: Background: Therapeutic drug monitoring is used to guide treatment in patients treated with TNF-α inhibitors. Current bridging ELISA (bELISA), mostly used in routine analysis, cannot detect anti-drug antibodies (ADA) in immune complexes and differentiate between… read more here.
Keywords: anti adl; belisa; bridging elisa; samples anti ... See more keywords