A cell-based assay for the detection of neutralizing antibodies against alemtuzumab
Sign Up to like & getrecommendations! Published in 2020 at "Biotechniques"
DOI: 10.2144/btn-2019-0122
Abstract: Aim: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective lymphocyte depletion in future treatment cycles. Results: Alemtuzumab–Alexa… read more here.
Keywords: anti alemtuzumab; assay detection; cell based; neutralizing antibodies ... See more keywords