Synthesis of syn- and enantioenriched anti-β-amino alcohols by highly diastereoselective borono-Mannich allylation reactions.
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DOI: 10.1039/d1cc06775c
Abstract: A highly diastereoselective method for the synthesis of syn-β-amino alcohols and enantioenriched anti-β-amino alcohols has been developed involving α-hydroxyl aldehydes and chiral α-phenylaminoxyaldehydes or α-benzoyloxyaldehydes, respectively in Petasis borono-Mannich allylation reactions. This study broadens the… read more here.
Keywords: synthesis syn; borono mannich; highly diastereoselective; anti amino ... See more keywords
Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of anti-1,2-amino alcohols.
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DOI: 10.1039/d2cc02317b
Abstract: Herein, we demonstrate the applicability of the 2,5-dimethylpyrrolo unit as a complementary N-protecting group in the highly diastereoselective synthesis of more than 20 different anti-amino alcohols (63-90% yields with up to 20 : 1 dr). Cleavage of… read more here.
Keywords: anti amino; synthesis; protecting group; amino ... See more keywords
Spinocerebellar Ataxia Type 31 Exacerbated by Anti-amino Terminal of Alpha-enolase Autoantibodies
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DOI: 10.2169/internalmedicine.8883-21
Abstract: We herein report a 61-year-old woman who was genetically diagnosed with spinocerebellar ataxia type 31 whose symptoms were modified by anti-amino terminal of alpha-enolase (NAE) antibodies, known as a biomarker of Hashimoto's encephalopathy (HE), and… read more here.
Keywords: anti amino; ataxia type; amino terminal; spinocerebellar ataxia ... See more keywords