Anti-amoebic potential of azole scaffolds and nanoparticles against pathogenic Acanthamoeba.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105618
Abstract: Acanthamoeba spp. are free living amoeba (FLA) which are widely distributed in nature. They are opportunistic parasites and can cause severe infections to the eye, skin and central nervous system. The advances in drug discovery… read more here.
Keywords: anti amoebic; potential azole; acanthamoeba; azole scaffolds ... See more keywords
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1149145
Abstract: Acanthamoeba species, Naegleria fowleri, and Balamuthia mandrillaris are opportunistic pathogens that cause a range of brain, skin, eye, and disseminated diseases in humans and animals. These pathogenic free-living amoebae (pFLA) are commonly misdiagnosed and have… read more here.
Keywords: anti amoebic; inhibitor chemotypes; novel anti; kinase inhibitor ... See more keywords
The Activity of Polyhomoarginine against Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11121726
Abstract: Simple Summary Acanthamoeba is free-living amoeba known to cause severe vision threatening eye infection. In most of the cases treating this infection is difficult due to the Acanthamoeba’s ability to switch between an active feeding… read more here.
Keywords: trophozoites cysts; activity; anti amoebic; acanthamoeba castellanii ... See more keywords
Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens"
DOI: 10.3390/pathogens9060476
Abstract: Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates > 90%. A number of constraints including misdiagnosis and partially effective treatments… read more here.
Keywords: balamuthia mandrillaris; response; castellanii; anti amoebic ... See more keywords