Anti‐Atherosclerotic Effects of Vitamins D and E in Suppression of Atherogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25738
Abstract: Atherosclerosis is a progressive and multifactorial disease which occurs under the influence of various risk factors including endothelial dysfunction (ED), oxidative stress, and low‐density lipoprotein (LDL) oxidation. In contract to the initial hypotheses on the… read more here.
Keywords: vitamins suppression; atherosclerotic effects; effects vitamins; anti atherosclerotic ... See more keywords
Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.12.028
Abstract: The sphingomyelin synthase 2 (SMS2) is a potential target for pharmacological intervention in atherosclerosis. However, so far, few selective SMS2 inhibitors and their pharmacological activities were reported. In this study, a class of 2-benzyloxybenzamides were… read more here.
Keywords: inhibitor; novel selective; anti atherosclerotic; atherosclerotic activities ... See more keywords
Secreted frizzled-related protein 4 exerts anti-atherosclerotic effects by reducing inflammation and oxidative stress.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174901
Abstract: Atherosclerosis and its sequelae, such as coronary artery disease (CAD), are the most common diseases worldwide and the leading causes of morbidity and mortality in most countries. Our previous studies have shown that circulating secreted… read more here.
Keywords: related protein; sfrp4; reducing inflammation; frizzled related ... See more keywords
The potential applications of mushrooms against some facets of atherosclerosis: A review.
Sign Up to like & getrecommendations! Published in 2018 at "Food research international"
DOI: 10.1016/j.foodres.2017.11.023
Abstract: Atherosclerosis is a complex pathology that involves several factors in its development, like oxidative stress, inflammation, hyperlipidemia, platelet aggregation and thrombus formation. Several drugs and therapeutic approaches have been developed to handle these aspects of… read more here.
Keywords: atherosclerotic effects; facets atherosclerosis; applications mushrooms; potential applications ... See more keywords
Anti‐atherosclerotic effect of Fermentum Rubrum and Gynostemma pentaphyllum mixture in high‐fat emulsion‐ and vitamin D3‐induced atherosclerotic rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Chinese Medical Association"
DOI: 10.1016/j.jcma.2017.08.018
Abstract: Background: The mixture of Hongqu and gypenosides (HG) is composed of Fermentum Rubrum (Hongqu, in Chinese) and total saponins of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan, in Chinese) in a 3.6:1 weight ratio. Both Hongqu and… read more here.
Keywords: hongqu; fermentum rubrum; atherosclerotic effect; gynostemma pentaphyllum ... See more keywords
Extract of radish (R. Sativus Linn) promotes anti-atherosclerotic effect using urine metabolomics in ApoE−/− mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104368
Abstract: Abstract Natural products such as Raphanus sativus Linn would be the potential candidate to benefit to atherosclerosis without side effects. Thus, this study aimed to investigate anti-atherosclerotic effect of radish extracts and to determine their… read more here.
Keywords: radish extract; atherosclerotic effect; anti atherosclerotic; radish extracts ... See more keywords
Evaluation of the haematinic, antioxidant and anti-atherosclerotic potential of Momordica charantia in cholesterol-fed experimental rats
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Reports"
DOI: 10.1016/j.toxrep.2022.03.042
Abstract: Background Momordica charantia is popularly used in folk medicine in the management of hyperlipidemia and atherosclerosis. Purpose To evaluate the anti-atherosclerotic potential of M. charantia as well as its haematinic and antioxidant potential. Methods Seventy-two… read more here.
Keywords: charantia; cholesterol; anti atherosclerotic; atherosclerotic potential ... See more keywords
Rational Design of Lovastatin-Loaded Spherical Reconstituted High Density Lipoprotein for Efficient and Safe Anti-Atherosclerotic Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00445
Abstract: Reconstituted high density lipoprotein (rHDL) is a biomimetic nanoparticle with plaque targeting and anti-atherosclerotic efficacy. In this work, we report on a strategy to rational design of lovastatin (LOV)-loaded spherical rHDL (LOV-s-rHDL) for efficient and… read more here.
Keywords: lov; effect; rational design; lov rhdl ... See more keywords
Dulaglutide exerts beneficial anti atherosclerotic effects in ApoE knockout mice with diabetes: the earlier, the better
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80894-x
Abstract: There has been no report about the mechanism for anti-atherosclerotic effects of dulaglutide (Dula) and/or about the difference of its effectiveness between in an early and a late phase of diabetes. To address such questions,… read more here.
Keywords: atherosclerotic effects; group; knockout mice; apoe knockout ... See more keywords
Abstract 493: Multidirectional Analysis of Anti-atherosclerotic Effect Caused by Korean Radish in Apo E–/– Mice Model
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.493
Abstract: Atherosclerosis, a leading cause of worldwide mortality and morbidity, is mainly controlled with statins, however, the statins have severe side effects like rhabdomyolysis. In search of an alternative for statin, we investigated anti-atherosclerotic and anti-hyperlipidemic… read more here.
Keywords: ganghwa radish; effect; model; anti atherosclerotic ... See more keywords
Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-021-02727-3
Abstract: Background Atherosclerosis is a chronic vascular disease posing a great threat to public health. We investigated whether rosuvastatin (RVS) enhanced autophagic activities to inhibit lipid accumulation and polarization conversion of macrophages and then attenuate atherosclerotic… read more here.
Keywords: polarization; polarization conversion; rvs; anti atherosclerotic ... See more keywords