Immune-mediated necrotizing myopathies and interstitial lung disease are predominant characteristics in anti-Ku positive patients with idiopathic inflammatory myopathies.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the rheumatic diseases"
DOI: 10.1136/annrheumdis-2020-217096
Abstract: We read an interesting study by Spielmann et al conducted on a single-centre large French cohort, which identified that anti-Ku autoantibodies were effective biomarkers for two distinct connective tissue diseases (CTDs): anti-Ku-positive patients with elevated… read more here.
Keywords: inflammatory myopathies; positive patients; anti autoantibodies; idiopathic inflammatory ... See more keywords
Association of Microglial Activation With Spontaneous ARIA-E and CSF Levels of Anti-Aβ Autoantibodies
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200892
Abstract: Background and Objectives Amyloid-related imaging abnormalities suggestive of vasogenic edema or sulcal effusion (ARIA-E) are the most common adverse events complicating Alzheimer disease (AD) immunotherapy with anti–β-amyloid (Aβ) monoclonal antibodies. ARIA-E can also occur spontaneously… read more here.
Keywords: csf levels; microglial activation; anti autoantibodies; levels anti ... See more keywords