Regioselective activation of benzocyclobutenones and dienamides lead to anti-Bredt bridged-ring systems by a [4+4] cycloaddition
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DOI: 10.1038/s41467-021-23344-0
Abstract: To the best of our knowledge, bridgehead carbon benzofused-bridged ring systems have previously not been accessible to the synthetic community. Here, we describe a formal type-II [4 + 4] cycloaddition approach that provides fully sp2-carbon embedded anti-Bredt… read more here.
Keywords: anti bredt; cycloaddition; ring systems; activation benzocyclobutenones ... See more keywords