Articles with "anti cd11b" as a keyword



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Preclinical ImmunoPET Imaging of Glioblastoma-Infiltrating Myeloid Cells Using Zirconium-89 Labeled Anti-CD11b Antibody

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Published in 2019 at "Molecular Imaging and Biology"

DOI: 10.1007/s11307-019-01427-1

Abstract: Purpose Glioblastoma is a lethal brain tumor, heavily infiltrated by tumor-associated myeloid cells (TAMCs). TAMCs are emerging as a promising therapeutic target as they suppress anti-tumor immune responses and promote tumor cell growth. Quantifying TAMCs… read more here.

Keywords: myeloid cells; cd11b antibody; cd11b; anti cd11b ... See more keywords
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Targeting Infiltrating Myeloid Cells in Gastric Cancer Using a Pretargeted Imaging Strategy Based on Bio-Orthogonal Diels-Alder Click Chemistry and Comparison with 89Zr-Labeled Anti-CD11b Positron Emission Tomography Imaging.

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Published in 2021 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.1c00745

Abstract: Gastric cancer (GC) is a common cancer worldwide, with high incidence and mortality rates. Therefore, early and precise diagnosis is critical to improving GC prognosis. Tumor-associated myeloid cells infiltrate the tumor microenvironment (TME) and can… read more here.

Keywords: myeloid cells; chemistry; cd11b; anti cd11b ... See more keywords

CD11b-Based Pre-Targeted SPECT/CT Imaging Allows for the Detection of Inflammation in Aortic Aneurysm

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Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s350593

Abstract: Purpose To investigate the feasibility of a pre-targeted imaging strategy based on the cycloaddition between 1,2,4,5-terazine (Tz) and trans-cyclooctene (TCO) for evaluating CD11b expression in inflammatory aortic aneurysm (AA) using single photon emission computed tomography/computed… read more here.

Keywords: cd11b; pre targeted; 99mtc hynic; anti cd11b ... See more keywords