Development of an Anti-CD99 Antibody Enables Targeting of Diffuse Midline Glioma.
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DOI: 10.1158/0008-5472.can-24-5027
Abstract: Diffuse midline gliomas (DMGs) are devastating brain tumors that occur primarily in children. The salient feature of these tumors is the presence of a H3K27M mutation (K27M), associated with the worst prognosis. Development of effective… read more here.
Keywords: dmgs; anti cd99; diffuse midline; development ... See more keywords
Abstract 2875: Targeted therapy of Ewing’s sarcoma by human anti CD99 targeted hybrid polymerized liposomal nanoparticles (HPLNs) encapsulating anticancer agents
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DOI: 10.1158/1538-7445.am2019-2875
Abstract: Most anticancer therapies are unspecific and therefore inevitably lead to off-target toxicity. To overcome these shortcomings, targetable hybrid polymerization liposomal nanoparticles (HPLNs) have been invented. Multiple innovative and proprietary technologies have been developed to enable… read more here.
Keywords: liposomal nanoparticles; hplns encapsulating; tumor; cd99 ... See more keywords