Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair
Sign Up to like & getrecommendations! Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.145380
Abstract: After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndrome (GI-ARS) lethality. While repurposing… read more here.
Keywords: anti ceramide; radiation syndrome; dna repair; repair ... See more keywords
495-P: Diabetic Retinopathy Is a Ceramidopathy Reversible by Systemic Anticeramide Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Diabetes"
DOI: 10.2337/db24-495-p
Abstract: Introduction: Diabetic retinopathy (DR) is characterized by retinal endothelial cell (REC) death and inadequate vascular repair by dysfunctional circulating angiogenic cells (CACs). We have previously demonstrated an increase in ASM-mediated C16 ceramide and ceramide-rich platform… read more here.
Keywords: vivo; ceramide abs; diabetic retinopathy; anti ceramide ... See more keywords
Ceramides in Autoimmune Rheumatic Diseases: Existing Evidence and Therapeutic Considerations for Diet as an Anticeramide Treatment
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DOI: 10.3390/nu15010229
Abstract: Autoimmune rheumatic diseases (AIRDs) constitute a set of connective tissue disorders and dysfunctions with akin clinical manifestations and autoantibody responses. AIRD treatment is based on a comprehensive approach, with the primary aim being achieving and… read more here.
Keywords: rheumatic diseases; anti ceramide; autoimmune rheumatic; ceramides autoimmune ... See more keywords