Arginase 1–Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti–PD-1 Checkpoint Blockade
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DOI: 10.1158/2326-6066.cir-21-0280
Abstract: ARG1-targeting vaccines are shown to activate antitumor immunity and modulate the tumor microenvironment in multiple tumor models without causing toxicity. The anti-tumor effect of ARG1 vaccines was boosted by anti–PD-1 checkpoint blockade, highlighting potential use… read more here.
Keywords: immunity; anti checkpoint; tumor; checkpoint blockade ... See more keywords