Detection of anti-citrullinated protein antibody (ACPA) in saliva for rheumatoid arthritis using DBA mice infected with Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104510
Abstract: OBJECTIVE The anti-citrullinated protein antibody (ACPA), an autoantibody of rheumatoid arthritis (RA), is very specific in the diagnosis of RA and has been detected in early cases and several years before the onset of the… read more here.
Keywords: arthritis; saliva; anti citrullinated; citrullinated protein ... See more keywords
Anti-citrullinated protein antibody profiles predict changes in disease activity in patients with rheumatoid arthritis initiating biologics.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead260
Abstract: OBJECTIVES To determine whether an expanded antigen-specific anti-citrullinated protein antibody (ACPA) profile predicts changes in disease activity in patients with rheumatoid arthritis (RA) initiating biologics. METHODS The study included participants from a prospective, non-randomized, observational… read more here.
Keywords: citrullinated protein; protein antibody; anti citrullinated; treatment ... See more keywords
Anti-citrullinated alpha enolase antibodies, interstitial lung disease and bone erosion in rheumatoid arthritis
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DOI: 10.1093/rheumatology/kex520
Abstract: Objectives RA is an articular chronic inflammatory disease that in a subgroup of patients can also present with extra-articular manifestations (EAMs). Despite intense investigation on this topic, reliable biomarkers for EAMs are lacking. In recent… read more here.
Keywords: disease; anti citrullinated; anti cep; alpha enolase ... See more keywords
Clinical relevance of rheumatoid factor and anti‐citrullinated peptides in fibrotic interstitial lung disease
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DOI: 10.1111/resp.14301
Abstract: Rheumatoid arthritis (RA) is a frequent cause of interstitial lung disease (ILD); however, the impact of rheumatoid factor and anti‐citrullinated peptide antibody seropositivity in ILD without connective tissue disease (CTD) is unclear. We examined the… read more here.
Keywords: factor anti; disease; rheumatoid factor; lung disease ... See more keywords
P113/O17 Human lymph node stromal cells express self-antigens targeted by anti-citrullinated protein antybodies: role for tolerance induction in rheumathoid arthritis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2019.101
Abstract: Career situation of first and presenting author Student for a master or a PhD. Introduction In rheumatoid arthritis (RA) the cause for loss of tolerance and anti–citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies… read more here.
Keywords: lymph node; expression; tolerance; anti citrullinated ... See more keywords
POS0465 DIFFERENT CLINICAL RELEVANCE OF ANTI-CITRULLINATED PROTEINS ANTIBODIES IN RA PATIENTS
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.2320
Abstract: Anti-citrullinated proteins antibodies (ACPA) are a broad group of antibodies, including antibodies to citrullinated fibrinogen, antibodies to cyclic citrullinated peptide (anti-CCP), antibodies to modified citrullinated vimentin (anti-MCV), antibodies to citrullinated α-enolase.To find a potential relationship… read more here.
Keywords: anti; anti mcv; anti ccp; anti citrullinated ... See more keywords
Current view on the pathogenic role of anti-citrullinated protein antibodies in rheumatoid arthritis
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DOI: 10.1136/rmdopen-2020-001228
Abstract: Epidemiological findings suggest a potential role for anti-citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) pathogenesis. ACPA-positive RA is associated with unique genetical and environmental risk factors, in contrast to seronegative RA. ACPA-positive healthy individuals… read more here.
Keywords: protein antibodies; anti citrullinated; citrullinated protein; role anti ... See more keywords
Corrigendum: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature
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DOI: 10.3389/fimmu.2021.710831
Abstract: [This corrects the article DOI: 10.3389/fimmu.2020.578848.]. read more here.
Keywords: citrullinated peptide; adult onset; onset anti; corrigendum adult ... See more keywords
The diagnostic and prognostic value of IgG and IgA anti-citrullinated protein antibodies in patients with early rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1096866
Abstract: Objectives Anti-citrullinated peptide antibodies (ACPA) are specific markers for rheumatoid arthritis (RA) and typically measured by assays employing a cyclic citrullinated peptide (CCP) as antigen. This study was aimed at investigating the diagnostic performance of… read more here.
Keywords: igg iga; iga; anti ccp2; anti citrullinated ... See more keywords
PAD4 Immunization Triggers Anti-Citrullinated Peptide Antibodies in Normal Mice: Analysis With Peptide Arrays
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.840035
Abstract: The critical immunological event in rheumatoid arthritis (RA) is the production of antibodies to citrullinated proteins (ACPAs), ie proteins on which arginines have been transformed into citrullines by peptidyl arginine deiminases (PAD). In C3H mice,… read more here.
Keywords: immunization; citrullinated peptide; anti citrullinated; mice ... See more keywords
Anti-citrullinated Protein Antibody Generation, Pathogenesis, Clinical Application, and Prospects
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DOI: 10.3389/fmed.2021.802934
Abstract: Anti-citrullinated protein antibodies (ACPAs) are autoantibodies commonly observed in patients with rheumatoid arthritis (RA). Currently, most of the mechanisms of ACPA formation and bone destruction are well-understood, however, some unknown mechanisms still exist. There have… read more here.
Keywords: application prospects; citrullinated protein; anti citrullinated; clinical application ... See more keywords