Interleukin-10 does not contribute to the anti-contractile nature of PVAT in health.
Sign Up to like & getrecommendations! Published in 2021 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2021.106838
Abstract: Perivascular adipose tissue (PVAT) is protective and reduces contraction of blood vessels in health. PVAT is composed of adipocytes, multiple types of immune cells and stromal cells. Interleukin (IL)-10, an anti-inflammatory cytokine usually produced by… read more here.
Keywords: nature pvat; contractile nature; pvat; anti contractile ... See more keywords
BETA3-ADRENOCEPTOR MEDIATED ADIPONECTIN SECRETION IS ESSENTIAL IN MODULATION OF VASCULAR TONE BY PERIVASCULAR ADIPOSE TISSUE
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000539033.54178.1d
Abstract: Objective: Healthy perivascular adipose tissue (PVAT) exerts an anti-contractile effect which is vital in regulating blood pressure. Evidence suggests that sympathetic nervous stimulation of PVAT triggers activation of adipocyte beta3-adrenoceptors, and the subsequent release of… read more here.
Keywords: contractile effect; beta3; adiponectin; pvat ... See more keywords
Lipoprotein lipase activation is a novel vascular anti-contractile mechanism that is lost in aging
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5730035
Abstract: Increasing incidence of cardiovascular events with age can be attributed to the natural deterioration in organ function, and manifests through a range of vascular phenotypes that include, endothelial dysfunction, hypercontractility, stiffening and remodeling, inflammation, and… read more here.
Keywords: effect; pvat; physiology; anti contractile ... See more keywords
Lipoprotein lipase underlies the vascular anti-contractile effect of perivascular adipose tissue (PVAT)
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731358
Abstract: Physiologically, perivascular adipose tissue (PVAT) exerts an anti-contractile effect on the vasculature. This effect is mediated by the biosynthesis and liberation of a myriad of anti-contractile molecules (e.g., adipokines). However, this anti-contractile function generally is… read more here.
Keywords: lipoprotein lipase; contractile effect; pvat; physiology ... See more keywords
Anti-Contractile and Anti-Inflammatory Effects of Diacerein on Isolated Mouse Airways Smooth Muscle and Mouse Asthma Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.560361
Abstract: Characterized by abnormal smooth muscle contractility and airway inflammation, asthma is one of the most common airway diseases worldwide. Diacerein is a well-known anti-inflammatory drug, widely used in osteoarthritis. In current study, the innovative usage… read more here.
Keywords: anti inflammatory; contractile anti; smooth muscle; mouse ... See more keywords