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Published in 2021 at "ESMO Open"
DOI: 10.1016/j.esmoop.2021.100061
Abstract: BRCA1 is a tumor-suppressor gene that encodes proteins involved in the repair of DNA double-strand breaks by way of the homologous recombination repair pathway. BRCA1 mutations occur in approximately 5% of breast cancer (BC) patients.…
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Keywords:
literature february;
anti csf1r;
february 2021;
treatment ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3287
Abstract: Stimulating innate immunity can potentially enable us to overcome resistance to PD-(L)1 blockade. We previously conducted a phase 1 trial of cabiralizumab (anti-CSF1R) with sotigalimab (CD40 agonistic antibody) and nivolumab. Our purpose was to determine…
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Keywords:
csf1r;
anti cd40;
anti csf1r;
anti anti ... See more keywords