Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection.
Sign Up to like & getrecommendations! Published in 2022 at "JCI insight"
DOI: 10.1172/jci.insight.158030
Abstract: The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,138 infants (age 6-12 weeks) and children (age… read more here.
Keywords: vaccination; igg; rts as01e; anti csp ... See more keywords
Correlations between three ELISA protocols measurements of RTS,S/AS01-induced anti-CSP IgG antibodies
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0286117
Abstract: Background RTS,S/AS01 induced anti-circumsporozoite protein (CSP) IgG antibodies are associated with the vaccine efficacy. There is currently no international standardisation of the assays used in the measurement of anti-CSP IgG antibody concentrations for use in… read more here.
Keywords: csp; igg antibodies; rts as01; anti csp ... See more keywords