Emergence of promising novel DPP‐4 inhibitory heterocycles as anti‐diabetic agents: A review
Sign Up to like & getrecommendations! Published in 2018 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201800127
Abstract: Diabetes has turned out to be an epidemic in the recent years all over the world, and today it has become a burden on the healthcare system. Over the years, with technological advancements, different classes… read more here.
Keywords: novel dpp; inhibitory heterocycles; anti diabetic; emergence promising ... See more keywords
In vitro enzymatic evaluation of some pyrazolo[1,5‐a]pyrimidine derivatives: Design, synthesis, antioxidant, anti‐diabetic, anti‐Alzheimer, and anti‐arthritic activities with molecular modeling simulation
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.22008
Abstract: The strategy of utilizing nitrogen compounds in various biological applications has recently emerged as a powerful approach to exploring novel classes of therapeutics to face the challenge of diseases. A series of pyrazolo[1,5‐a]pyrimidine‐based compounds 3a–l… read more here.
Keywords: anti alzheimer; pyrazolo pyrimidine; anti diabetic; diabetic anti ... See more keywords
Molecular Interaction of Anti‐Diabetic Drugs With Acetylcholinesterase and Sodium Glucose Co‐Transporter 2
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26036
Abstract: Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD) are the two disorders which are known to share pertinent pathological and therapeutic links. Sodium glucose co‐transporter‐2 (SGLT2) and Acetylcholinesterase (AChE) are established inhibition targets for… read more here.
Keywords: sodium glucose; glucose transporter; diabetic drugs; anti diabetic ... See more keywords
Anti-diabetic drugs and sarcopenia: emerging links, mechanistic insights, and clinical implications.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12838
Abstract: Sarcopenia, characterized by loss of skeletal muscle mass, quality, and strength, has become a common hallmark of ageing and many chronic diseases. Diabetes mellitus patients have a higher prevalence of sarcopenia, which greatly aggravates the… read more here.
Keywords: sarcopenia; diabetic drugs; clinical implications; muscle mass ... See more keywords
Evaluation of Na and K in anti-diabetic ayurvedic medicine using LIBS
Sign Up to like & getrecommendations! Published in 2021 at "Lasers in Medical Science"
DOI: 10.1007/s10103-021-03289-y
Abstract: Diabetes mellitus, known as diabetes, is a challenging issue, and to control diabetes, a large population is lining toward ayurvedic medicine. In the present study, four brands of anti-diabetic ayurvedic medicines, along with a home… read more here.
Keywords: medicine; evaluation anti; medicine using; diabetic ayurvedic ... See more keywords
Anti-diabetic vanadyl complexes reduced Alzheimer’s disease pathology independent of amyloid plaque deposition
Sign Up to like & getrecommendations! Published in 2018 at "Science China Life Sciences"
DOI: 10.1007/s11427-018-9350-1
Abstract: Association of Alzheimer’s disease (AD) with cerebral glucose hypometabolism, likely due to impairments of insulin signaling, has been reported recently, with encouraging results when additional insulin is provided to AD patients. Here, we tested the… read more here.
Keywords: alzheimer disease; anti diabetic; vanadyl complexes; pathology ... See more keywords
Polymeric Precipitation Inhibitor–Based Solid Supersaturable SMEDD Formulation of Canagliflozin: Improved Bioavailability and Anti-diabetic Activity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-020-09445-1
Abstract: Purpose The current investigation explores the enhanced biopharmaceutical attributes of solid supersaturable self-microemulsifying drug delivery system (Solid SS SMEDDS) for poorly water soluble drug canagliflozin (CFZ). Methods Solid SS SMEDD formulation was prepared by spray drying… read more here.
Keywords: solid supersaturable; precipitation inhibitor; smedd formulation; formulation ... See more keywords
Role of medicinal plants in the management of diabetes mellitus: a review
Sign Up to like & getrecommendations! Published in 2018 at "3 Biotech"
DOI: 10.1007/s13205-018-1528-0
Abstract: Medicinal plants have a vast potential in the treatment of various ailments due to the presence of therapeutically important phytochemicals. Diabetes is a serious metabolic disorder and several marketed medications are available to alleviate the… read more here.
Keywords: plants management; anti diabetic; plants anti; review ... See more keywords
Development and screening of byproduct for its secondary metabolites, antioxidant and anti-diabetic potential from anthracnose-infected fruits of pomegranate: a sustainable approach
Sign Up to like & getrecommendations! Published in 2021 at "3 Biotech"
DOI: 10.1007/s13205-020-02629-z
Abstract: The main focus of the present study was to analyze the antioxidant and anti-diabetic potential of fermentative byproduct, developed from anthracnose-infected pomegranate fruits. The analysis of fermented juice showed a reduction in total phenolic content,… read more here.
Keywords: antioxidant anti; anti diabetic; diabetic potential; juice ... See more keywords
Nanoparticulate-based drug delivery systems for small molecule anti-diabetic drugs: An emerging paradigm for effective therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.09.049
Abstract: Emergence of nanoparticulate drug delivery systems in diabetes has facilitated improved delivery of small molecule drugs which could dramatically improve the quality of life for diabetics. Conventional dosage forms of the anti-diabetic drugs exhibit variable/less… read more here.
Keywords: nanotechnology; drug delivery; delivery; anti diabetic ... See more keywords
Anti-diabetic, hepatoprotective and antioxidant potential of Brassica oleracea sprouts
Sign Up to like & getrecommendations! Published in 2020 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2020.101623
Abstract: Abstract The aim of this study and experiments was to estimate the anti-diabetic and hepatoprotective effect of Brassica oleracea sprouts extract in streptozotocin induced diabetic rats. Diabetes is induced in rats by intra-peritoneal injection of… read more here.
Keywords: oleracea sprouts; brassica oleracea; anti diabetic; diabetic hepatoprotective ... See more keywords