Anti-domain 1 of beta2-glycoprotein I aids risk stratification in lupus anticoagulant-positive patients
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-019-00555-w
Abstract: Lupus anticoagulant (LA) is considered a risk factor for thromboembolism (TE) and adverse pregnancy outcomes (APOs). However, quite a few patients diagnosed with LA positivity do not suffer these adverse events. Further testing of anticardiolipin… read more here.
Keywords: risk; positive patients; beta2 glycoprotein; anti domain ... See more keywords
Structure of Blood Coagulation Factor VIII in Complex with an Anti-C1 Domain Pathogenic Antibody Inhibitor.
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DOI: 10.1182/blood.2020008940
Abstract: Antibody inhibitor development in hemophilia A represents the most significant complication resulting from factor VIII (fVIII) replacement therapy. Recent studies have demonstrated that epitopes present in the C1 domain contribute to a pathogenic inhibitor response.… read more here.
Keywords: inhibitor; antibody inhibitor; structure; anti domain ... See more keywords