Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris
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DOI: 10.1016/j.celrep.2018.07.093
Abstract: SUMMARY Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and DSG1 autoantibodies are predominantly of the IgG4 subclass and less frequently… read more here.
Keywords: pemphigus vulgaris; disease pemphigus; iga; autoimmune disease ... See more keywords