N-doped carbon dots modified with the epithelial cell adhesion molecule antibody as an imaging agent for HepG2 cells using their ultra-sensitive response to Al3.
Sign Up to like & getrecommendations! Published in 2020 at "Nanotechnology"
DOI: 10.1088/1361-6528/abb0b5
Abstract: Carbon dots (CDs) are emerging as an ideal multifunctional materials due to their ease of preparation and excellent properties in medical imaging technology, environmental monitoring, chemical analysis and other fields. N-doped CDs modified with the… read more here.
Keywords: modified epithelial; cell adhesion; anti epcam; carbon dots ... See more keywords
Facile Synthesis of NaYF4:Yb Up-Conversion Nanoparticles Modified with Photosensitizer and Targeting Antibody for In Vitro Photodynamic Therapy of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/4470510
Abstract: Rare Earth up-conversion nanoparticles NaYF4:20%Yb,2%Er@PEI (UCNPs) were generated via a one-step hydrothermal technique at relatively reduced temperatures. Photosensitizer Ce6 and anti-EpCAM, a highly expressed monoclonal antibody in cancer stem cells of hepatocellular carcinoma, were linked… read more here.
Keywords: hepatocellular carcinoma; ce6; conversion; anti epcam ... See more keywords
Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale Research Letters"
DOI: 10.1186/s11671-020-03334-9
Abstract: In this study, we have surface-functionalized PEGylated-nanoliposomal doxorubicin (DOX) with anti-EpCAM (epithelial cell adhesion molecule) aptamer via post-insertion of anti-EpCAM aptamer-conjugated DSPE-mPEG 2000 into Caelyx® (ED-lip). The size, charge, release profile, and cytotoxicity and cellular… read more here.
Keywords: c26; anti epcam; lip; epcam aptamer ... See more keywords
A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG2a-f) Exerts Antitumor Activity in Xenograft Model
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DOI: 10.3390/antib11040074
Abstract: The epithelial cell adhesion molecule (EpCAM) is a stem cell and carcinoma antigen, which mediates cellular adhesion and proliferative signaling by the proteolytic cleavage. In contrast to low expression in normal epithelium, EpCAM is frequently… read more here.
Keywords: cell; epmab mg2a; mg2a; anti epcam ... See more keywords
Potential Use of CTCs as Biomarkers in Renal Cancer Patients
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DOI: 10.3390/life12010089
Abstract: We demonstrated that the CellCollector is an appropriate tool for detecting CTCs in RCC patients. We examined EpCAM and MUC1 expression levels in RCC tissues and cell lines and analyzed the detection rate of CTCs… read more here.
Keywords: ctcs biomarkers; use ctcs; potential use; ctcs ... See more keywords
Antitumor activities of a defucosylated anti-EpCAM monoclonal antibody in colorectal carcinoma xenograft models
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2023.5221
Abstract: Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein, which is highly expressed on tumor cells. As EpCAM plays a crucial role in cell adhesion, survival, proliferation, stemness, and tumorigenesis, it has been… read more here.
Keywords: epcam monoclonal; tumor; anti epcam; epmab mg2a ... See more keywords