Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effects of FcRn Inhibitors in Mice, Rats, and Monkeys.
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DOI: 10.1016/j.xphs.2018.10.065
Abstract: There is a growing interest in developing inhibitors of the neonatal Fc-receptor, FcRn, for use in the treatment for humoral autoimmune conditions. We have developed a new physiologically based pharmacokinetic model that is capable of… read more here.
Keywords: based pharmacokinetic; mice rats; anti fcrn; physiologically based ... See more keywords