Anti-FGFR3 antibody epitopes are functional sites and correlate with the neuropathy pattern
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577757
Abstract: Antibodies against FGFR3 define a subgroup of sensory neuropathy (SN). The aim of this study was to identify the epitope(s) of anti-FGFR3 autoantibodies and potential epitope-dependent clinical subtypes. Using SPOT methodology, five specific candidate epitopes,… read more here.
Keywords: sites correlate; fgfr3 antibody; antibody epitopes; functional sites ... See more keywords
Sensory neuronopathies, diagnostic criteria and causes
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001105
Abstract: Purpose of review To stress on the diagnostic strategy of sensory neuronopathies (SNN), including new genes and antibodies. Recent finding SNN involve paraneoplastic, dysimmune, toxic, viral and genetic mechanisms. About one-third remains idiopathic. Recently, new… read more here.
Keywords: snn; anti fgfr3; sensory neuronopathies; anti ago ... See more keywords