Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19 ?
Sign Up to like & getrecommendations! Published in 2020 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2020.109843
Abstract: Abstract SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19.Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority.… read more here.
Keywords: treat covid; anti filarial; covid; drug diethylcarbamazine ... See more keywords
Deciphering the anti-filarial potential of bioactive compounds from Ocimum sanctum: a combined experimental and computational study
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2132030
Abstract: Abstract Context The anthelminthic effect of Ocimum species (Lamiaceae) has been reported, however, its anti-filarial effect has not been explored to date. Objective This study evaluates the effect of Ocimum sanctum L. (OS) against lymphatic… read more here.
Keywords: bioactive compounds; effect; sanctum; anti filarial ... See more keywords
In Vitro and In Silico Studies of Glycyrrhetinic acid derivatives as Anti-Filarial Agents.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026619666190618141450
Abstract: BACKGROUND Lymphatic filariasis continues to be one of the major health problems in tropical and subtropical countries despite the use of standard drugs diethylcarbamazine and ivermectin because they are microfilaricides with poor or no activity… read more here.
Keywords: glycyrrhetinic acid; anti filarial; silico studies; vitro silico ... See more keywords