Nonparaneoplastic Anti-GAD Limbic Encephalitis: Seizure Outcome and Long-term Neuropsychological Follow-up After Immunotherapy
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DOI: 10.1097/wnn.0000000000000313
Abstract: Antibodies against glutamate decarboxylase (GAD-Abs), especially GAD65 antibodies, are associated with limbic encephalitis (LE) manifested by temporal lobe epilepsy and neuropsychological deficits. We present the case of a 42-year-old Greek woman with nonparaneoplastic anti-GAD LE,… read more here.
Keywords: long term; gad; limbic encephalitis; immunotherapy ... See more keywords
The association of basal insulin treatment versus standard care with outcomes in anti‐GAD positive and negative subjects: A post‐hoc analysis of the ORIGIN trial
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DOI: 10.1111/dom.13528
Abstract: We compared cardiovascular and other outcomes in patients with dysglycaemia with or without anti‐glutamic acid dehydrogenase (GAD) antibodies participating in the Outcome Reduction with Initial Glargine Intervention (ORIGIN) trial. Of the 12 537 participants, 8162… read more here.
Keywords: anti gad; origin trial; gad positive; standard care ... See more keywords
Rare presentation of anti-GAD-65 antibody-positive autoimmune encephalitis and simultaneous onset of type 1 diabetes mellitus in a paediatric patient
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DOI: 10.1136/bcr-2020-237913
Abstract: A 16-year-old female patient presented with subacute onset of headaches, changes in acute mental status, expressive aphasia and auditory hallucinations. New oedema and enhancement of the temporal lobe were seen on brain MRI, with correlating… read more here.
Keywords: anti gad; onset; type diabetes; onset type ... See more keywords
Neurological Syndromes Associated with Anti-GAD Antibodies
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DOI: 10.3390/ijms21103701
Abstract: Glutamic acid decarboxylase (GAD) is an intracellular enzyme whose physiologic function is the decarboxylation of glutamate to gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter within the central nervous system. GAD antibodies (Ab) have been associated… read more here.
Keywords: gad; syndromes associated; neurological syndromes; gad antibodies ... See more keywords
Gut Microbiota Functional Traits, Blood pH, and Anti-GAD Antibodies Concur in the Clinical Characterization of T1D at Onset
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DOI: 10.3390/ijms231810256
Abstract: Alterations of gut microbiota have been identified before clinical manifestation of type 1 diabetes (T1D). To identify the associations amongst gut microbiome profile, metabolism and disease markers, the 16S rRNA-based microbiota profiling and 1H-NMR metabolomic… read more here.
Keywords: blood; anti gad; t1d onset; gut microbiota ... See more keywords
'Primary progressive multiple sclerosis overlapping with anti-GAD and anti-Hu antibodies positive neurological syndromes' - clinical considerations.
Sign Up to like & getrecommendations! Published in 2022 at "Neurologia i neurochirurgia polska"
DOI: 10.5603/pjnns.a2022.0028
Abstract: I was interested to read the case reports published in the Polish Journal of Neurology and Neurosurgery entitled: ‘Primary progressive multiple sclerosis overlapping with anti-GAD and anti-Hu antibodies positive neurological syndromes’ by Štourač et al.… read more here.
Keywords: primary progressive; progressive multiple; neurology; csf ... See more keywords