The level of naturally occurring anti‐αGal antibody predicts antibody response to polysaccharide vaccination in HIV‐infected adults
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13008
Abstract: In clinical practice, the capacity for producing anti‐carbohydrate antibodies is regarded as an entity, but supportive evidence is lacking. We hypothesized that the outcome of the gold standard test for clinical assessment of this capacity,… read more here.
Keywords: polysaccharide vaccination; antibody; level; anti gal ... See more keywords
Cytokine profile associated with selective removal of natural anti-αGal antibodies in a sepsis model in Gal-KO mice
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297917020122
Abstract: Selective depletion of natural anti-Galα1-3Galβ1-4GlcNAc (so-called anti-αGal) antibodies is achieved in α1,3-galactosyltransferase knockout (Gal-KO) mice by administration of the soluble glycoconjugate of αGal GAS914. This molecule removed up to 90% of natural circulating anti-αGal antibodies… read more here.
Keywords: gal; gal antibodies; cytokine profile; anti gal ... See more keywords
Antibody Dependent Enhancement of Infections after High Dose Chemotherapy
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DOI: 10.1182/blood-2019-122236
Abstract: Background: High dose chemotherapy (HDT) burdens patients with a high risk of serious infections while neutropenic. The role of host antibodies as risk factors for infections is unclear. Our aim was to investigate if pre-HDT… read more here.
Keywords: infectious episodes; gal; antibody; serum ... See more keywords
AGI-134: a fully synthetic α-Gal glycolipid that converts tumors into in situ autologous vaccines, induces anti-tumor immunity and is synergistic with an anti-PD-1 antibody in mouse melanoma models
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cell International"
DOI: 10.1186/s12935-019-1059-8
Abstract: BackgroundTreatments that generate T cell-mediated immunity to a patient’s unique neoantigens are the current holy grail of cancer immunotherapy. In particular, treatments that do not require cumbersome and individualized ex vivo processing or manufacturing processes… read more here.
Keywords: anti antibody; melanoma models; anti gal; agi 134 ... See more keywords
Exploring the Ecological Implications of Microbiota Diversity in Birds: Natural Barriers Against Avian Malaria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.807682
Abstract: Natural antibodies (Abs), produced in response to bacterial gut microbiota, drive resistance to infection in vertebrates. In natural systems, gut microbiota diversity is expected to shape the spectrum of natural Abs and resistance to parasites.… read more here.
Keywords: microbiota diversity; anti gal; avian malaria; gal abs ... See more keywords
Poly-L-Lysine-Based αGal-Glycoconjugates for Treating Anti-αGal IgE-Mediated Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.873019
Abstract: Anti-αGal IgE antibodies mediate a spreading allergic condition known as αGal-syndrome (AGS). People exposed to hard tick bites are sensitized to αGal, producing elevated levels of anti-αGal IgE, which are responsible for AGS. This work… read more here.
Keywords: gal ige; anti gal; gal glycoconjugates; ige antibodies ... See more keywords
Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (Spheniscus humboldti)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.897223
Abstract: Aspergillosis is a fungal infection caused mainly by Aspergillus fumigatus that often results in respiratory disease in birds. Aspergillosis is a major cause of morbidity and mortality in captive-bred penguin species. Currently, there is no… read more here.
Keywords: anti gal; humboldt penguins; infection; aspergillosis ... See more keywords