Erodium birandianum Ilarslan & Yurdak. shows anti-gout effect through xanthine oxidase inhibition: Combination of in vitro and in silico techniques and profiling of main components by LC-Q-ToF-MS
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DOI: 10.1016/j.phytol.2021.03.010
Abstract: Abstract The anti-gout effect of Erodium birandianum Ilarslan & Yurdak. was investigated through xanthine oxidase (XO) inhibition using in vitro and in silico experiments. The ethanol extract of E. birandianum (EB) with 82.26 ± 0.10… read more here.
Keywords: anti gout; erodium birandianum; gout effect; effect ... See more keywords
Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
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DOI: 10.1038/s41421-025-00779-z
Abstract: Gout, a common and painful disease, stems from hyperuricemia, where elevated blood urate levels lead to urate crystal formation in joints and kidneys. The human urate transporter 1 (hURAT1) plays a critical role in urate… read more here.
Keywords: urate transport; mechanisms urate; inhibition; anti gout ... See more keywords
Host‐directed anti‐mycobacterial activity of colchicine, an anti‐gout drug, via strengthened host innate resistance reinforced by the IL‐1β/PGE2 axis
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15838
Abstract: To diversify and expand possible tuberculosis (TB) drug candidates and maximize limited global resources, we investigated the effect of colchicine, an FDA‐approved anti‐gout drug, against Mycobacterium tuberculosis (Mtb) infection because of its immune‐modulating effects. read more here.
Keywords: host directed; anti gout; colchicine; host ... See more keywords
Potential anti-gout properties of Wuwei Shexiang pills based on network pharmacology and pharmacological verification.
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DOI: 10.2139/ssrn.4272755
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Wuwei Shexiang Pills (WWSX), a classic Tibetan medicine, consists of Chebulae Fructus (removed pit), Aucklandiae Radix, Moschus, Aconiti Fiavi Radix, and Acori Calami Rhizoma. It is used clinically in China to treat joint… read more here.
Keywords: anti gout; pharmacology; gout; wwsx ... See more keywords
Total Phenolic content and Potential of Black Betel Leaf (Piper betle L.var Nigra) Extract as an Antioxidant and Anti-Gout
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DOI: 10.52711/0974-360x.2024.00176
Abstract: Research to find antioxidants and anti-gout has been done using black betel leaf. The sample was extracted at room temperature for 30 minutes using the Ultrasound-Assisted Extraction (UAE) method, and a yield of 8.47% was… read more here.
Keywords: black betel; betel leaf; anti gout; betel ... See more keywords