Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.01.015
Abstract: Human epididymis protein 4 (HE4) is a glycoprotein secreted by epithelial ovarian cancer (EOC) cells and is a novel and specific biomarker for diagnosing and prognosing EOC. Previous studies have shown that overexpression of HE4… read more here.
Keywords: epididymis protein; human epididymis; he4; anti he4 ... See more keywords
Development of fluorescence/MR dual-modal manganese-nitrogen-doped carbon nanosheets as an efficient contrast agent for targeted ovarian carcinoma imaging
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-020-00736-w
Abstract: Background Development of sensitive and specific imaging approaches for the detection of ovarian cancer holds great promise for improving the therapeutic efficacy and the lifespan of the patients. Results In this study, manganese-nitrogen doped carbon… read more here.
Keywords: carcinoma; anti he4; fluorescence dual; dual modal ... See more keywords