Identification of novel N-acetylcysteine derivatives for the treatment of hepatocellular injury.
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DOI: 10.1039/c7md00409e
Abstract: New anti-hepatocellular injury drugs with better curative effects and fewer side effects are urgently needed at present. In this study, a series of novel N-acetylcysteine (NAC) derivatives were designed, synthesized and biologically evaluated for their… read more here.
Keywords: cell; hepatocellular injury; identification novel; anti hepatocellular ... See more keywords
Anti-hepatocellular carcinoma activities of novel hydrazone derivatives via downregulation of interleukin-6
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DOI: 10.1039/d4ra05854b
Abstract: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related morbidity worldwide. Sorafenib is a first-line drug for the treatment of HCC, however, it is reported to cause serious adverse effects and may lead… read more here.
Keywords: hepatocellular carcinoma; downregulation interleukin; anti hepatocellular; hydrazone derivatives ... See more keywords
Preliminary Evaluation of Artificial Intelligence-Based Anti-Hepatocellular Carcinoma Molecular Target Study in Hepatocellular Carcinoma Diagnosis Research
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DOI: 10.1155/2022/8365565
Abstract: In this paper, in-depth research analysis of anti-hepatocellular carcinoma molecular targets for hepatocellular carcinoma diagnosis was conducted using artificial intelligence. Because BRD4 plays an important role in gene transcription for cell cycle regulation and apoptosis,… read more here.
Keywords: hepatocellular carcinoma; anti hepatocellular; carcinoma molecular; brd4 ... See more keywords
Synthesis of Cucurbitacin B Derivatives as Potential Anti-Hepatocellular Carcinoma Agents
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DOI: 10.3390/molecules23123345
Abstract: Cucurbitacin B shows potent activity against tumor cells, but its high toxicity limits its application in the clinic. A series of cucurbitacin B derivatives was synthesized and evaluated for their anti-hepatocellular carcinoma (HCC) activities against… read more here.
Keywords: hepatocellular carcinoma; cell line; compound; cucurbitacin derivatives ... See more keywords