Efficacy of plasmapheresis and semi‐selective immunoadsorption for removal of anti‐HLA antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21858
Abstract: In organ transplantation, apheresis is frequently used for removal of anti‐HLA antibodies. However, it is unclear whether plasmapheresis (PP) or semi‐selective immunoadsorption (IA) should be employed, and the optimal number of apheresis sessions required to… read more here.
Keywords: plasmapheresis semi; selective immunoadsorption; hla antibodies; semi selective ... See more keywords
Down syndrome with neonatal alloimmune thrombocytopenia due to anti-HLA A31 and B61 antibodies
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03092-z
Abstract: Neonatal alloimmune thrombocytopenia (NAIT) arises from fetomaternal platelet incompatibility that results in transplacental passage of maternal antibodies mostly against fetal human platelet antigens (HPA), whereas NAIT due to anti-human leukocyte antigen (HLA) antibodies is extremely… read more here.
Keywords: alloimmune thrombocytopenia; hla antibodies; hla; neonatal alloimmune ... See more keywords
P112 Impact of allele-specific anti-HLA class I antibodies on organ allocation
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.172
Abstract: Aim Accurate classification of serologically-distinct antigens (Ag) is critical in organ allocation, and nowadays it is possible to define anti-HLA antibody specificity to the allelic level. We examined class I antibodies (Ab) for allelic specificities… read more here.
Keywords: class; hla; organ allocation; allele specific ... See more keywords
HLA epitopes - Empirically defined as conformational amino acids sequences of the HLA antigen and are likely to be part of the binding sites of anti-HLA antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "Human immunology"
DOI: 10.1016/j.humimm.2021.12.004
Abstract: Antibodies against HLA antigens are ubiquitous in the sera of transplant patients. Analysis of anti-HLA antibodies specificity has gone through a long history of development using assays like agglutination and lymphocytotoxicity, which utilize lymphocytes, and… read more here.
Keywords: anti hla; hla antibodies; hla antigens; hla epitopes ... See more keywords
Allo-immunisation anti-HLA et transfusion plaquettaire
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion Clinique et Biologique"
DOI: 10.1016/j.tracli.2018.08.084
Abstract: La transfusion de concentres de plaquettes (CP) prophylactique ou curative peut etre suivie d’une inefficacite transfusionnelle voire d’un etat refractaire (ER). Les patients recevant de maniere chronique des CP sont exposes a ces risques. Les… read more here.
Keywords: transfusion; immunisation anti; immunisation; allo immunisation ... See more keywords
Frequency of Human Leukocyte Antigens and Donor Specific Antibodies in Long-Term Living Donor Kidney Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2019.01.195
Abstract: PURPOSE HLA antibodies have been shown to be associated with late graft loss. In this study, we defined the incidence and profiles of anti-HLA antibodies and their impact on graft outcome in long-term kidney recipients.… read more here.
Keywords: presence; class; hla antibodies; anti hla ... See more keywords
Antibody response to HBV vaccination on dialysis does not correlate with the development of deNovo anti-HLA antibodies after renal transplantation.
Sign Up to like & getrecommendations! Published in 2017 at "Transplant immunology"
DOI: 10.1016/j.trim.2017.04.003
Abstract: BACKGROUND Response to Hepatitis B virus (HBV) vaccination can be diminished in some (50-80%) but not all dialysis patients. We hypothesized, that the response to vaccination on dialysis may correlate with the development of anti-HLA… read more here.
Keywords: response; hbv vaccination; hla antibodies; anti hla ... See more keywords
Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Platelets"
DOI: 10.1080/09537104.2022.2129604
Abstract: Immune-mediated platelet refractoriness (PR) remains a significant problem in the setting of platelet transfusion and is predominantly caused by the presence of alloantibodies directed against class I human leukocyte antigens (HLA). Opsonization of donor platelets… read more here.
Keywords: derived macrophages; phagocytosis; monocyte derived; anti hla ... See more keywords
Heart transplantation and antibody-mediated rejection: role of myocardial strain as an early marker of cardiac dysfunction in patients with anti-HLA antibody
Sign Up to like & getrecommendations! Published in 2021 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehab724.0961
Abstract: Antibody-mediated rejection of the transplanted heart is still currently diagnosed by endomyocardial biopsy whereas clinical elements, anti-Human Leukocite Antigens (HLA) antibody and graft dysfunction represents supplementary components. The aim of the study was to identify… read more here.
Keywords: heart; rejection; antibody; strain ... See more keywords
P6314Left- versus Bi-Ventricular Assist Device-mediated anti-HLA alloantibody induction in bridge-to-transplantation patients
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0911
Abstract: Presence of anti-Human Leukocyte Antigen (anti-HLA) alloantibodies (allosensitization) in a heart transplantation candidate impedes the chance of finding a compatible transplant. Left Ventricular Assist Devices (LVADs) have been shown to induce allosensitization. The purpose of… read more here.
Keywords: bivad patients; lvad bivad; hla; transplantation ... See more keywords
Elimination of Anti-HLA Alloantibody Producing B Cells through the Use of a CAR-Like HLA Molecule in T Cells
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation"
DOI: 10.1097/01.tp.0000520318.94454.cb
Abstract: Introduction: T cell immunotherapy using Chimeric AntigenReceptors (CA to generate tumor antigen-specific effector T cells has achieved excellent re in anti-leukemic clinical trials, and in a broader appraisal, promising immuno apeutic results. Amajor problem in… read more here.
Keywords: hla molecule; car like; hla; car ... See more keywords