HMGB1‐induced inflammatory response promotes bone healing in murine tooth extraction socket
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26710
Abstract: High mobility group box 1 (HMGB1) is a non‐histone DNA‐binding protein that is secreted into the extracellular milieu in response to inflammatory stimuli. The secreted HMGB1 has been suggested to mediate various inflammatory diseases. However,… read more here.
Keywords: hmgb1; tooth extraction; extraction socket; anti hmgb1 ... See more keywords
HMGB1/anti-HMGB1 antibodies define a molecular signature of early stages of HIV-Associated Neurocognitive Disorders (HAND)
Sign Up to like & getrecommendations! Published in 2017 at "Heliyon"
DOI: 10.1016/j.heliyon.2017.e00245
Abstract: Background HIV-associated neurocognitive disorders (HAND) persist in the post-HAART era, characterized by asymptomatic neurocognitive impairment (ANI) and mild neurocognitive disorders (MND). High mobility group box 1 (HMGB1) is a non-histone chromosomal protein widely expressed in… read more here.
Keywords: hmgb1; hmgb1 igg; anti hmgb1; hand ... See more keywords
Anti-High Mobility Group Box 1 Antibody Therapy May Prevent Cognitive Dysfunction After Traumatic Brain Injury.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.10.164
Abstract: BACKGROUND High mobility group box 1 (HMGB1) protein plays a key role in triggering inflammatory responses in many diseases. Our previous study showed that HMGB1 is found upstream of secondary damage in traumatic brain injury… read more here.
Keywords: anti hmgb1; hmgb1 mab; brain; injury ... See more keywords
Lipidomics Study of Sepsis-Induced Liver and Lung Injury under Anti-HMGB1 Intervention.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00851
Abstract: Sepsis usually leads to lethal multiorgan dysfunction including acute liver failure (ALF) and acute lung injury (ALI). This research sought to reveal the lipid alteration of anti-high mobility group box 1 (HMGB1) treatment in sepsis-induced… read more here.
Keywords: lung injury; anti hmgb1; sepsis induced; hmgb1 ... See more keywords
Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation
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DOI: 10.1186/s10020-019-0081-6
Abstract: BackgroundExtracellular high mobility group box 1 protein (HMGB1) serves a central role in inflammation as a transporter protein, which binds other immune-activating molecules that are endocytosed via the receptor for advanced glycation end-products (RAGE). These pro-inflammatory… read more here.
Keywords: hmgb1; hmgb1 antagonist; antagonist box; anti hmgb1 ... See more keywords
Effects of subconjunctival administration of anti-high mobility group box 1 on dry eye in a mouse model of Sjӧgren’s syndrome
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DOI: 10.1371/journal.pone.0183678
Abstract: Purpose Extracellular high mobility group box 1 (HMGB1) acts as a damage associated molecular pattern molecule through the Toll-like receptor to promote autoreactive B cell activation, which may be involved in the pathogenesis of Sjӧgren’s… read more here.
Keywords: gren syndrome; administration anti; dry eye; anti hmgb1 ... See more keywords