Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope
Sign Up to like & getrecommendations! Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.11.056
Abstract: Summary The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell… read more here.
Keywords: anti idiotypic; antibody; reactive anti; broadly reactive ... See more keywords
Generation of panels of anti-idiotypic single-chain variable fragments mimicking Cry2Aa toxin using the chain shuffling technique
Sign Up to like & getrecommendations! Published in 2018 at "Food and Agricultural Immunology"
DOI: 10.1080/09540105.2018.1440535
Abstract: ABSTRACT Here, we firstly reported to generate panels of anti-idiotypic single-chain variable fragments (scFvs) of Bacillus thuringiensis Cry2Aa toxin by chain shuffling method. Light- and heavy-chain-shuffled libraries based on two parental clones were constructed. The… read more here.
Keywords: chain; anti idiotypic; panels anti; cry2aa toxin ... See more keywords
The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-21-0220
Abstract: To this day, multiple myeloma remains an incurable cancer. For many patients, recurrence is unavoidably a result of lacking treatment options in the minimal residual disease stage. This is due to residual and treatment-resistant myeloma… read more here.
Keywords: myeloma; medicine; patient specific; anti idiotypic ... See more keywords
Detection of antibodies against benzo[a]pyrene in blood sera of lung cancer patients by ELISA using human recombinant idiotypic and anti-idiotypic antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental oncology"
DOI: 10.32471/exp-oncology.2312-8852.vol-43-no-4.17126
Abstract: Aim of this study was to develop and apply an ELISA method for assessment of the levels of endogenous antibodies against benzo[a]pyrene (Bp) in blood sera of lung cancer (LC) patients. MATERIALS AND METHODS ELISA… read more here.
Keywords: idiotypic antibodies; idiotypic anti; idiotypic; anti idiotypic ... See more keywords
Anti-Idiotypic Antibodies Specific to prM Monoantibody Prevent Antibody Dependent Enhancement of Dengue Virus Infection
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00157
Abstract: Dengue virus (DENV) co-circulates as four serotypes (DENV1-4). Primary infection only leads to self-limited dengue fever. But secondary infection with another serotype carries a higher risk of increased disease severity, causing life-threatening dengue hemorrhagic fever/dengue… read more here.
Keywords: anti idiotypic; denv; infection; prm ... See more keywords
Nanobodies Selectively Binding to the Idiotype of a Dengue Virus Neutralizing Antibody Do Not Necessarily Mimic the Viral Epitope
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030551
Abstract: Vaccination against dengue virus is challenged by the fact that a generic immune response can induce antibody-dependent-enhancement (ADE) in secondary infections. Only some antibodies targeting a quaternary epitope formed by the dimerization of the virus… read more here.
Keywords: epitope; neutralizing antibody; dengue virus; virus ... See more keywords