Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections.
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DOI: 10.1016/j.biomaterials.2022.121461
Abstract: Emerging antimicrobial resistance in infections asks for novel intervention strategies. Galacto-oligosaccharides (GOS) might be attractive alternatives to antibiotics due to their anti-inflammatory and anti-adhesive properties. Mannheimia haemolytica is one of the major Pasteurellaceae associated with… read more here.
Keywords: lung; anti bacterial; galacto oligosaccharides; anti invasive ... See more keywords
Vehicle development, pharmacokinetics and toxicity of the anti-invasive agent 4-fluoro-3’,4’,5’-trimethoxychalcone in rodents
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DOI: 10.1371/journal.pone.0192548
Abstract: Effective inhibitors of invasion and metastasis represent a serious unmet clinical need. We have recently identified 4-fluoro-3’,4’,5’-trimethoxychalcone or C16 as a potent anti-invasive molecule. In this paper, we report on the development of an optimized… read more here.
Keywords: anti invasive; vehicle; fluoro trimethoxychalcone; development ... See more keywords
The Use of Naphthoquinones and Furano-naphthoquinones as Antiinvasive Agents.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666171006131927
Abstract: BACKGROUND Cancer is a leading cause of mortality in the world and metastasis is to blame. A number of naphthoquinones (NQs) have shown ability to reduce cancer stemness and metastatic potential. Furano-naphthoquinones (FNQs), which is… read more here.
Keywords: furano naphthoquinones; mechanisms nqs; fnqs; cancer ... See more keywords