Gold and silver nanoparticles functionalized with 4',7-dihydroxyflavone exhibits activity against Leishmania donovani.
Sign Up to like & getrecommendations! Published in 2022 at "Acta tropica"
DOI: 10.1016/j.actatropica.2022.106448
Abstract: Leishmaniasis is a neglected tropical disease that has been burdening the world for over a century. Though there are drugs to treat leishmaniasis, the repertoire suffers several drawbacks like toxicity and low therapeutic value. Therefore,… read more here.
Keywords: 47dhf 47dhf; gold silver; activity; silver nanoparticles ... See more keywords
Lupeol and amphotericin B mediate synergistic anti-leishmanial immunomodulatory effects in Leishmania donovani-infected BALB/c mice.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155319
Abstract: Leishmania donovani, a protozoan parasite, inflicts the disease Visceral leishmaniasis (VL) Worldwide. The only orally bioavailable drug miltefosine is toxic, whereas liposomal amphotericin B (AmpB) is expensive. Lupeol, a triterpenoid from Sterculia villosa bark, was… read more here.
Keywords: leishmanial immunomodulatory; anti leishmanial; lupeol; immunomodulatory effects ... See more keywords
Design, synthesis and biological evaluation of piperazinyl-β-carbolinederivatives as anti-leishmanial agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.03.022
Abstract: Molecular hybridization is a ligand based drug design approach is well known recent medicinal chemistry to design anti-parasitic agents. In the present study, we have designed a series of (1-phenyl-9H-pyrido [3,4-b]indol-3-yl) (4-phenylpiperazin-1-yl)methanone derivatives using molecular… read more here.
Keywords: design synthesis; leishmanial activity; anti leishmanial; chemistry ... See more keywords
Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An update
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04916
Abstract: Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy. The treatment for the Leishmaniasis is not up to… read more here.
Keywords: leishmaniasis; anti leishmanial; carboline; recent evolution ... See more keywords
Anti-leishmanial activity and cytotoxicity of a series of tris-aryl Sb(V) mandelate cyclometallate complexes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2019.110932
Abstract: A series of ten cyclometallates and two μ2-peroxo bridged tris-aryl Sb(V) complexes derived from R/S-mandelic acid (= R/S-ManH2) were synthesised and characterised. As confirmed by X-ray crystallography the complexes 1Sr/s, [Sb(o-tol)3(man)], 2Sr/s, [Sb(m-tol)3(man)], 4Sr/s, [Sb(o-PhOMe)3(man)],… read more here.
Keywords: anti leishmanial; man; tris aryl; series ... See more keywords
Effect of functionalities on the crystal structures of new zinc(II) dithiocarbamates: a combined anti-leishmanial and thermal decomposition study
Sign Up to like & getrecommendations! Published in 2017 at "CrystEngComm"
DOI: 10.1039/c7ce00211d
Abstract: New homoleptic zinc(II) dithiocarbamates, [Zn(L)2] (L = N-ferrocenyl-N-methyl dithiocarbamate (L1) 1, (N-(benzo[d][1,3]dioxol-5-ylmethyl)-N-furfuryl) dithiocarbamate (L2) 2, N-(benzo[d][1,3]dioxol-5-ylmethyl)-(N-benzyl) dithiocarbamate (L3) 3, N-(benzo[d][1,3]dioxol-5-ylmethyl)-(N-methyl) dithiocarbamate (L4) 4, N-ethylmorpholine-(N-4-methoxyphenylmethyl) dithiocarbamate (L5) 5 and N-(benzo[d][1,4]dioxol-6-ylmethyl)-(N-benzylmethyl) dithiocarbamate (L6) 6, have been synthesized… read more here.
Keywords: anti leishmanial; dioxol ylmethyl; benzo dioxol; dithiocarbamate ... See more keywords
Impact of substituents on the crystal structures and anti-leishmanial activity of new homoleptic Bi(iii) dithiocarbamates
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj04477a
Abstract: Anti-leishmanial activity of six structurally characterised new functionalised homoleptic Bi(iii) dithiocarbamate complexes having monomeric, dimeric and rare polymeric structures has been explored. read more here.
Keywords: leishmanial activity; anti leishmanial; impact substituents; homoleptic iii ... See more keywords
Density functional studies of antimony complexes derived from carboxamide ligands
Sign Up to like & getrecommendations! Published in 2023 at "Materials Research Express"
DOI: 10.1088/2053-1591/acd2ac
Abstract: The anti-leishmanial activity of antimony (III) complexes [1a-3a] bearing carboxamide ligands has been reported in the literature. In this study, a complete assignment of the vibrational spectra of these complexes was performed using the Scaled… read more here.
Keywords: studies antimony; carboxamide ligands; functional studies; antimony complexes ... See more keywords
Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-021-00853-0
Abstract: As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to systemic immersion causing hyperthermic hepato-splenomegaly. Curbing leishmanial parasite is toughly attributable… read more here.
Keywords: anti leishmanial; delivery; nano dds; drug ... See more keywords
Peganum harmala and Nigella sativa: anti-leishmanial activity against Leishmania major promastigotes and amastigotes: in vitro and ex vivo experiment.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of parasitology"
DOI: 10.17420/ap6702.344
Abstract: Leishmaniosis is one of the most important vectors borne disease that is endemic in tropical and subtropical areas. There are many approved treatment for different types of leishmaniosis but all are with some adverse side… read more here.
Keywords: sativa; anti leishmanial; promastigotes amastigotes; vitro vivo ... See more keywords
In Vitro Anti-Leishmanial Assessment of Some Medicinal Plants Collected from Al Qassim, Saudi Arabia.
Sign Up to like & getrecommendations! Published in 2020 at "Acta Parasitologica"
DOI: 10.2478/s11686-020-00205-2
Abstract: PURPOSE In the present work, a group of nine medicinal plants (Sonchus oleraceus, Echinops spinosissimus, Trichodesma africana, Pergularia tomentosa, Teucrium oliverianum, Blepharis ciliaris, Citrllus colocynthis, Cleome amblyocarpa and Aerva javanica) from eight different families were… read more here.
Keywords: saudi arabia; vitro anti; plants collected; medicinal plants ... See more keywords