P135 Association of Serum Anti-Muscarinic 3 Antibodies with Gastrointestinal Disease in Systemic Sclerosis
Sign Up to like & getrecommendations! Published in 2024 at "Rheumatology"
DOI: 10.1093/rheumatology/keae163.175
Abstract: Gastrointestinal (GI) complications of systemic sclerosis (SSc) are frequent and debilitating with symptoms ranging from reflux to faecal soilage. The pathogenesis of GI disease in SSc is poorly understood. Circulating antibodies against Muscarinic type 3… read more here.
Keywords: m3r; disease; ssc patients; anti m3r ... See more keywords
Anti-muscarinic 3 antibodies associate with a severe clinical phenotype in patients with systemic sclerosis.
Sign Up to like & getrecommendations! Published in 2025 at "Rheumatology"
DOI: 10.1093/rheumatology/keaf197
Abstract: OBJECTIVES Functional antibodies play a role in SSc gastrointestinal (GI) disease, but their clinical relevance is unclear. We examined GI and extraintestinal features associated with anti-M3R antibodies in SSc patients. METHODS In a cohort enriched… read more here.
Keywords: severity; high titer; anti m3r; m3r antibodies ... See more keywords