Dermatopulmonary Syndrome Associated With Anti-MDA5 Antibodies After Allogeneic Hematopoietic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2016.3976
Abstract: Importance Chronic graft-vs-host-disease (cGVHD) after allogeneic stem cell transplantation (AHSCT) may resemble autoimmune diseases. Anti-MDA5 (melanoma differentiation–associated gene 5) dermatopulmonary syndrome is a subset of dermatomyositis defined by specific clinical features and detection of anti-MDA5-antibodies… read more here.
Keywords: clinical features; anti mda5; cell transplantation; mda5 antibodies ... See more keywords
Serum KL‐6 level is a prognostic marker in patients with anti‐MDA5 antibody‐positive dermatomyositis associated with interstitial lung disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22978
Abstract: This study aimed to investigate the clinical significance of Krebs von den Lungen‐6 (KL‐6) serum levels in patients with anti‐MDA5 antibody‐positive dermatomyositis (anti‐MDA5+ DM) having interstitial lung disease (ILD), especially in the amyopathic DM phenotype. read more here.
Keywords: positive dermatomyositis; anti mda5; antibody positive; interstitial lung ... See more keywords
Serum YKL-40 level is associated with severity of interstitial lung disease and poor prognosis in dermatomyositis with anti-MDA5 antibody
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04457-w
Abstract: ObjectiveWe aimed to investigate the clinical value of checking serum chitinase-3-like-1 protein (YKL-40) levels in anti-MDA5 antibody-positive dermatomyositis (anti-MDA5+DM) patients.MethodsOne hundred and five consecutive anti-MDA5+DM patients and 44 healthy controls were enrolled in this study.… read more here.
Keywords: anti mda5; serum ykl; interstitial lung; mda5 patients ... See more keywords
A RAPIDLY PROGRESSIVE AND RARE ILLNESS: AUTOANTIBODIES AGAINST MELANOMA DIFFERENTIATION-ASSOCIATED PROTEIN 5 (ANTI-MDA5): AMYOPATHIC DERMATOMYOSITIS WITH PROGRESSIVE INTERSTITIAL LUNG DISEASE THAT DEVELOPED AFTER COVID-19 VACCINE
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DOI: 10.1016/j.chest.2021.07.646
Abstract: TOPIC: Critical Care TYPE: Global Case Reports INTRODUCTION: Anti-MDA5 dermatomyositis is a subtype of dermatomyositis characterized by a high risk of rapidly progressive interstitial lung disease. It is characterized by fever, progressive shortness of breath,… read more here.
Keywords: anti mda5; progressive interstitial; lung disease; interstitial lung ... See more keywords
Anti-MDA5 antibody-positive rapidly progressive interstitial pneumonia without cutaneous manifestations
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DOI: 10.1016/j.rmcr.2019.01.012
Abstract: A 47-year-old man was referred to our hospital with a 1-month history of fever and dyspnea after inhalation of insecticide in a confined space. We diagnosed rapidly progressive interstitial pneumonia. High-dose methylprednisolone, tacrolimus, and intermittent… read more here.
Keywords: anti mda5; rapidly progressive; antibody positive; mda5 antibody ... See more keywords
Acute lung injury after plasma exchange in a patient with anti-MDA5 antibody-positive, rapidly progressive, interstitial lung disease：A case report
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DOI: 10.1016/j.rmcr.2020.101016
Abstract: The presence of anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab) is closely associated with rapidly progressive interstitial lung disease (RP-ILD) in patients with clinically amyopathic dermatomyositis. Despite intensive immunosuppressive therapies, some of these patients still… read more here.
Keywords: anti mda5; acute lung; report; lung injury ... See more keywords
Clinical features of dermatomyositis associated with anti-MDA5 antibodies by age
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DOI: 10.1080/14397595.2020.1740400
Abstract: Abstract Objectives Anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody-positive and age at onset ≥60 years are poor prognosis factors in polymyositis (PM) and dermatomyositis (DM) associated with interstitial lung disease (ILD) among Japanese patients. However, the… read more here.
Keywords: clinical features; anti mda5; age; dermatomyositis associated ... See more keywords
Anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease – a case report
Sign Up to like & getrecommendations! Published in 2018 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2017.1420521
Abstract: Abstract Case presentation: We present a case of a 55-year-old Caucasian male with manifestations of dermatomyositis complicated with rapidly progressive interstitial lung disease (RP-ILD). Diagnosis of anti-MDA5 positive dermatomyositis was made. Discussion: Myositis specific antibodies… read more here.
Keywords: anti mda5; lung disease; case; interstitial lung ... See more keywords
The characteristics of lymphocytes in patients positive for anti-MDA5 antibodies in interstitial lung disease.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa266
Abstract: OBJECTIVE The aim was to investigate the characteristics of blood lymphocytes in patients positive for anti-melanoma differentiation-associated gene 5 antibodies (anti-MDA5+) in interstitial lung disease. METHODS Thirty-eight anti-MDA5+ patients with interstitial lung disease were admitted… read more here.
Keywords: cd8; anti mda5; lung disease; interstitial lung ... See more keywords
Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America.
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DOI: 10.1093/rheumatology/keaa429
Abstract: OBJECTIVE Myositis-specific autoantibodies have defined distinct phenotypes of patients with juvenile myositis (JIIM). We assessed the frequency and clinical significance of anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody-associated JIIM in a North American registry. METHODS Retrospective… read more here.
Keywords: autoantibody; anti mda5; mda5 autoantibodies; jiim ... See more keywords
Forced vital capacity predicts the survival of interstitial lung disease in anti-MDA5 positive dermatomyositis: a multi-centre cohort study.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab305
Abstract: OBJECTIVES Anti-melanoma differentiation-associated gene 5 (MDA5) positive dermatomyositis (DM) is a life-threatening disease often complicated with rapidly progressive interstitial lung disease (ILD). This study aimed to establish and validate a clinical prediction model for 6-month… read more here.
Keywords: anti mda5; centre; study; disease ... See more keywords