Anti-MEK and Anti-EGFR mAbs in RAS-Mutant Metastatic Colorectal Cancer: Case Series and Rationale
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DOI: 10.1007/s12325-019-00949-y
Abstract: KRAS (Kirsten rat sarcoma viral oncogene) or BRAF (v-raf murine sarcoma viral oncogene homolog B1) constitutive activation leads to anti-EGFR (epidermal growth factor receptor) therapy resistance of metastatic colorectal cancer patients. In this article we… read more here.
Keywords: metastatic colorectal; anti mek; colorectal cancer; anti egfr ... See more keywords