The synergistic effect of maltose enhances the anti-melanogenic activity of acarbose
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-017-1717-4
Abstract: Melanocytes play an important role in maintaining epidermal homeostasis by producing melanin and protecting the skin from harmful environmental factors. However, excessive up- or down-regulation of melanin production often causes hyper- or hypo-pigmented disorders, respectively,… read more here.
Keywords: activity; melanogenic activity; anti melanogenic; synergistic effect ... See more keywords
Anti-melanogenic effect of gomisin N from Schisandra chinensis (Turcz.) Baillon (Schisandraceae) in melanoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-017-0903-4
Abstract: Overproduction and accumulation of melanin in the skin can lead to pigmentation disorders, such as freckles and melasma. Many researchers are studying the regulation of melanogenesis in the skin with the aim of developing whitening… read more here.
Keywords: gomisin; melanoma cells; chinensis turcz; turcz baillon ... See more keywords
Anti-melanogenic activity of schaftoside in Rhizoma Arisaematis by increasing autophagy in B16F1 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.06.021
Abstract: Skin pigmentation involves multiple processes, including melanin synthesis, transport, and melanosome release. Melanin content determines skin color and protects against UV radiation-induced damage. Autophagy is a cooperative process between autophagosomes and lysosomes that degrades cellular… read more here.
Keywords: rhizoma arisaematis; b16f1 cells; melanogenic activity; schaftoside ... See more keywords
Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2017.03.011
Abstract: BACKGROUND Microphthalmia-associated transcription factor (MITF) suppresses the expression of enzymes controlling the production of melanin. Phytosphingosine is a well-known cosmetic agent, but its anti-melanogenic activity and mechanism of action remain unclear. OBJECTIVE This study was… read more here.
Keywords: transcription; mitf; phytosphingosine; melanogenic activity ... See more keywords
Anti-melanogenic effects of oyster hydrolysate in UVB-irradiated C57BL/6J mice and B16F10 melanoma cells via downregulation of cAMP signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.09.036
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Pacific oyster (Crassostrea gigas) has been used to treat pigmentary disorders such as freckles, melasma, and moles in Korea. AIM OF THE STUDY We aimed to investigate the inhibitory effects of oyster hydrolysate… read more here.
Keywords: via downregulation; downregulation camp; mice; anti melanogenic ... See more keywords
D-tyrosine adds an anti-melanogenic effect to cosmetic peptides
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-019-57159-3
Abstract: D-tyrosine is known to negatively regulate melanin synthesis by inhibiting tyrosinase activity. Here, we further reveal that peptides containing terminal D-tyrosine can reduce the melanin contents of human melanocytes. The addition of D-tyrosine to the… read more here.
Keywords: cosmetic peptides; tyrosine; adds anti; melanogenic effect ... See more keywords
Gamma-Irradiated Luteolin Inhibits 3-Isobutyl-1-Methylxanthine-Induced Melanogenesis Through the Regulation of CREB/MITF, PI3K/Akt, and ERK Pathways in B16BL6 Melanoma Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medicinal Food"
DOI: 10.1089/jmf.2016.3890
Abstract: Luteolin was gamma irradiated at doses of 0, 15, 30, 50, 70, and 100 kGy. We observed that the luteolin peak decreased simultaneously with the appearance of new radiolytic peaks, using high-performance liquid chromatography (HPLC). The… read more here.
Keywords: pi3k; isobutyl methylxanthine; irradiated luteolin; gamma irradiated ... See more keywords
Tiered approach for evaluation of anti‐melanogenic activity of trans‐N‐coumaroyltyramine derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14569
Abstract: Skin hyperpigmentation is commonly treated by topical drug application. Several naturally occurring compounds exhibit attractive biological effects including anti‐melanogenic activity. Chemically modified derivatives of those compounds are expected to be more efficient. However, efficacy and… read more here.
Keywords: tiered approach; activity; activity trans; anti melanogenic ... See more keywords
Anti-melanogenic activity of Viola odorata different extracts on B16F10 murine melanoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2017.8350
Abstract: Objective(s): In previous studies, antioxidant activity of Viola odorata L. has been demonstrated. In this study, we have investigated the anti-melanogenic effect of extract and fractions of the plant in B16F10 cell line. Materials and… read more here.
Keywords: viola odorata; activity viola; anti melanogenic; tyrosinase ... See more keywords
Phenotype-based screening of selected mangrove methanolic crude extracts with anti-melanogenic activity using zebrafish (Danio rerio) as a model
Sign Up to like & getrecommendations! Published in 2017 at "Scienceasia"
DOI: 10.2306/scienceasia1513-1874.2017.43.163
Abstract: Novel skin hypopigmenting agents are important due to the unwanted side effects of existing therapies and treatments. In this study, the melanogenic effects of crude extracts of selected mangroves, namely, Avicennia marina, Excoecaria agallocha, Rhizophora… read more here.
Keywords: using zebrafish; phenotype based; model; crude extracts ... See more keywords
Identification of a Novel Class of Anti-Melanogenic Compounds, (Z)-5-(Substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one Derivatives, and Their Reactive Oxygen Species Scavenging Activities
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11050948
Abstract: The rate-determining role of tyrosinase makes it a critical component in the mechanism that is responsible for melanogenesis. Thirteen (Z)-5-(substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one ((Z)-BPTT) analogs were designed based on the structural features of two potent tyrosinase inhibitors,… read more here.
Keywords: phenyl thioxothiazolidin; benzylidene phenyl; substituted benzylidene; tyrosinase ... See more keywords